Grant Gives New Breath to Patients Suffering from Severe Pulmonary Hypertension

Nearly $8 million grant helps launch a nationwide patient registry to improve CTEPH practices

Imagine trying to take a deep breath, but feeling like you’re sucking air through a straw. That’s how some patients with chronic thromboembolic pulmonary hypertension (CTEPH) describe living with the condition, which is estimated to affect several thousand Americans yearly but is commonly misdiagnosed. UC San Diego Health System is a world leader in CTEPH, and now with a $7.6 million grant, has helped launch the first national CTEPH registry to improve best practices and patient care. … Read the full story from the UC San Diego Newsroom


Dr. Kim KerrPrincipal Investigator of the project is Kim Kerr, MD, professor of clinical medicine in the Division of Pulmonary and Critical Care Medicine. She directs the Medical Intensive Care Unit at UC San Diego Health System’s Thornton Hospital in La Jolla.

Dr. Michael MadaniCardiac surgeon Michael Madani, MD, co-investigator, is chief of cardiothoracic surgery and director of UC San Diego Sulpizio Cardiovascular Center – Surgery.

Anti-Leukemia Drug May Also Work Against Ovarian Cancer

An antibody therapy already in clinical trials to treat chronic lymphocytic leukemia (CLL) may also prove effective against ovarian cancer – and likely other cancers as well, report researchers at the University of California, San Diego School of Medicine in a study published in the Nov. 17 online early edition of the Proceedings of the National Academy of Sciences (PNAS).

The findings extend the anti-cancer potential of an experimental monoclonal antibody called cirmtuzumab, developed at UC San Diego Moores Cancer Center by Thomas Kipps, MD, PhD, and colleagues. Cirmtuzumab is currently in a first-in-human phase 1 clinical trial to assess its safety and efficacy in treating CLL. … Read the full story from the UC San Diego Newsroom


Dr. Thomas Kipps

Dr. Thomas Kipps

Thomas Kipps, MD, PhD, Evelyn and Edwin Tasch Chair in Cancer Research, is professor of medicine in the Division of Hematology-Oncology and deputy director of research at the UC San Diego Moores Cancer Center.

Dr. Kipps directs the multi-institutional, National Institutes of Health (NIH)-sponsored CLL Research Consortium (CRC) and UC San Diego Blood Cancer Research Fund.

Dr. Joseph M. Vinetz Presents CPC on Chronic GI Bleeding in Ethiopian Man at November 12 Medicine Grand Rounds

Dr. Joseph VinetzChronic gastrointestinal bleeding in a 50-year-old man from Ethiopia is the topic of a clinicopathological conference to be presented by Dr. Joseph M. Vinetz at Medicine Grand Rounds on November 12.

Joseph M. Vinetz, MD, is professor of medicine in the Division of Infectious Diseases, Department of Medicine at the UCSD School of Medicine. He is associate editor of the American Journal of Tropical Medicine and Hygiene and deputy editor of PLoS Neglected Tropical Diseases.

Training the Next Generation of Cancer Scientists

National Cancer Institute training grant has supported UC San Diego scholars since 1984

The University of California, San Diego received a $2.5 million Institutional Ruth L. Kirschstein National Research Service Award from the National Cancer Institute (NCI), part of the National Institutes of Health (NIH), to support four predoctoral and six postdoctoral scholars in the campus’s cancer training program. First awarded in 1984, the grant is the single longest-running NCI training grant at UC San Diego. The 2014 grant renewal will provide funding through 2019, when it will have completed 34 years of training for cancer investigators…. Read the full story from the UC San Diego Newsroom

More about the UC San Diego NIH/NCI Cancer Training Grant

Dr. Thomas Savides Speaking on Recent Advances in Endoscopy at This Week’s Grand Rounds

Dr. Thomas Savides, the founder and director of the Endoscopic Ultrasound Program at UC San Diego Health System, will speak on recent advances in endoscopy at this week’s session of Medicine Grand Rounds.

Thomas J. Savides, MD, is professor of clinical medicine in the Division of Gastroenterology and executive vice chair of the Department of Medicine.

Earlier this year, he was named chief experience officer for UC San Diego Health System.

See his clinical profile

Plasmapheresis for Medical Disorders: Dr. Amber Paratore Sanchez Speaking at This Week’s Grand Rounds

Dr. Amber SanchezDr. Amber Sanchez will speak on plasmapheresis for medical disorders at the October 22 session of Medicine Grand Rounds.

A former UC San Diego chief medical resident (2006-2007) who is now on the internal medicine faculty, Amber Paratore Sanchez, MD, is Health Sciences assistant clinical professor in the Division of Nephrology-Hypertension.

She is associate medical director of the Therapeutic Apheresis Program at UC San Diego Health System.

See her clinical profile

Dr. Lindia Willies-Jacobo on Promoting Health Equity: The Role of Diversity and Cultural Competency at Medicine Grand Rounds October 15

Lindia Willies-Jacobo, MDDr. Lindia Willies-Jacobo will present on promoting health equity at this week’s session of Medicine Grand Rounds.

Lindia Willies-Jacobo, MD, FAAP, is clinical professor of pediatrics and assistant dean for Diversity and Community Partnerships at the UC San Diego School of Medicine. She directs the Program in Medical Education – Health Equity (PRIME-HEq).

See Dr. Willies-Jacobo’s clinical profile

Big Data Sharing for Better Health

Researchers at University of California, San Diego School of Medicine have been awarded a $9.2 million grant to help modernize and transform how researchers share, use, find and cite biomedical datasets.

The 3-year project, in collaboration with The University of Texas Health Science Center at Houston, is part of a federal initiative to increase the utility of biomedical research data, launched this week by the National Institutes of Health (NIH) through its Big Data to Knowledge (BD2K) program. … Read the full story from the UC San Diego Newsroom


Dr. Lucila Ohno-MachadoLucila Ohno-Machado, MD, PhD, is lead investigator on the Biomedical and healthCAre Data Discovery and Indexing Ecosystem (BioCADDIE) project.

Dr. Ohno-Machado, professor of medicine, is founding chief of the Division of Biomedical Informatics.

Read the BioCADDIE project description on the NIH RePORTER

UC San Diego Part of New Effort to Fight Autoimmune Disorders

Major multi-year partnership will focus first on rheumatoid arthritis and lupus

The Division of Rheumatology, Allergy and Immunology at University of California, San Diego School of Medicine has been named a key site in a national, multi-institution, multi-year $41.6 million program to speed drug discovery, development, diagnostics and therapies for patients with autoimmune disorders, primarily rheumatoid arthritis (RA) and lupus erythematosus, which affect millions of Americans. …Read the full story from the UC San Diego Newsroom

Dr. Karl Hostetler on Discovery and Development of Brincidofovir (DNA Viruses) and 1968(HPV 16&18) October 1

Dr. Karl HostetlerDr. Karl Hostetler presents on the topic, “Discovery and Development of Brincidofovir (DNA Viruses) and 1968 (HPV 16&18)” at Medicine Grand Rounds on October 1.

Karl Hostetler, MD, is emeritus professor of medicine in the Division of Infectious Diseases at UC San Diego.