Potency of Statins Linked to Muscle Side Effects

A study from the University of California, San Diego School of Medicine, published August 22 online by PLoS ONE, reports that muscle problems reported by patients taking statins were related to the strength or potency of the given cholesterol-lowering drugs. … Read the full story from the UCSD Newsroom


Dr. Beatrice Golomb led the study team. Beatrice Golomb, MD, PhD, is professor of medicine in the Division of General Internal Medicine.More information:

  • Citation for the new study: Hoffman KB, Kraus C, Dimbil M, Golomb BA. A survey of the FDA’s AERS database regarding muscle and tendon adverse events linked to the statin drug class. PLoS One. 2012;7(8):e42866. doi: 10.1371/journal.pone.0042866. Epub 2012 Aug 22. Abstract
  • Related study: Statins Shown to Cause Fatigue

Statins Shown to Cause Fatigue

In a study of more than 1,000 adults, researchers at the University of California, San Diego, found that individuals taking cholesterol-lowering statin drugs are more likely than non-users to experience decreased energy, fatigue upon exertion, or both. The researchers suggest that these findings should be taken into account by doctors when weighing risk versus benefit in prescribing statins. … Read the full story from the UCSD Newsroom


More information:

  • Read the article in Archives of Internal Medicine
    Online First: June 11. 2012: Arch Intern Med. 2012;():1-2. doi:10.1001/archinternmed.2012.2171
  • Citation for Publication: Golomb BA, Evans MA, Dimsdale JE, White HL. Effects of statins on energy and fatigue with exertion: results from a randomized controlled trial. Arch Intern Med. Published online August 13, 2012. doi:10.1001/archinternmed.2012.2171..

Cholesterol-Lowering Statins Boost Bacteria-Killing Cells

Widely prescribed for their cholesterol-lowering properties, recent clinical research indicates that statins can produce a second, significant health benefit: lowering the risk of severe bacterial infections such as pneumonia and sepsis… Read the full story from the UCSD Newsroom

Christopher K. Glass, M.D., Ph.D.

Department of Medicine coauthors on the published paper are Anna L. Kogen, Ph.D., Richard Gallo, M.D., Ph.D., Professor of Medicine and Pediatrics and Chief of the Division of Dermatology; and corresponding author Christopher K. Glass, M.D., Ph.D. (pictured above), Professor of Medicine in the Division of Endocrinology and Metabolism and Professor of Cellular and Molecular Medicine.

Read the published study (PDF).

In the Media: Dr. Joseph Witztum

Dr. Joseph Witztum is a quoted expert in the Scientific American story, “Static over Statins: Should Young People Without Cholesterol Problems Take Statins?”

Joseph L. Witztum, M.D., is Professor of Medicine in the Division of Endocrinology and Metabolism.

In the Media: Dr. Beatrice Golomb

Dr. Beatrice Golomb is one of the experts quoted in the article, “Do Statins Work Equally for Men and Women?” in Time magazine.

Beatrice Golomb, M.D., Ph.D., is Associate Professor of Medicine in General Internal Medicine.