New Study Upends Thinking About How Liver Disease Develops

In the latest of a series of related papers, researchers at the University of California, San Diego School of Medicine, with colleagues in Austria and elsewhere, present a new and more definitive explanation of how fibrotic cells form, multiply and eventually destroy the human liver, resulting in cirrhosis… Read the full story from the UCSD Newsroom

Pictured above is David Brenner, MD, Vice Chancellor for Health Sciences and dean of the UC San Diego School of Medicine, who is senior author of the research report.  First author of the study is Dr. Christoph H. Österreicher of the Biomedical Genomics (BIOGEM) Microarray Facility in the UCSD Department of Medicine, the Laboratory of Gene Regulation and Signal Transduction in the UCSD Department of Pharmacology, and the Medical University of Vienna. Other Department of Medicine coauthors are Drs. Melitta Penz-Österreicher (Medical University of Vienna), Roman Šášik, and BIOGEM director Dr. Gary Hardiman.

Read the report in the Proceedings of the National Academy of Sciences.