Powerful Approach to the Analysis of Protein Motions

DXMS analysis provides novel tool for studying how movements allow proteins to perform their functions as molecular machines

Researchers at the University of California, San Diego School of Medicine and the University of Texas Medical Branch (UTMB) in Galveston have concluded a study that offers a new understanding of the role that motions, or dynamics, play in the functioning of the protein Epac2. Their work provides information likely to help scientists design drugs to battle major diseases in which Epac2 plays a role, such as diabetes and cancer. … Read the full story from the UCSD Newsroom

Virgil L. Woods, Jr., MD

The study’s UC San Diego principal investigator is Virgil L. Woods, Jr., MD, Professor of Medicine in the Division of Rheumatology, Allergy and Immunology (pictured). First author Sheng Li, PhD, is chief scientist in the UCSD DXMS Proteomics Resource.