Biologists Use Flies and Mice to Get to the Heart of Down Syndrome

A novel study involving fruit flies and mice has allowed biologists to identify two critical genes responsible for congenital heart defects in individuals with Down syndrome, a major cause of infant mortality and death in people born with this genetic disorder. … Read the full story from the UCSD Newsroom


M. Geoff Rosenfeld, MD   Dr. Kirk Peterson

UC San Diego collaborators in this multi-center effort are Drs. Amir Gamliel, M. Geoff Rosenfeld and Kirk L. Peterson. M. Geoffrey Rosenfeld, MD, above left, is professor of medicine in the Division of Endocrinology and Metabolism and a Howard Hughes Medical Institute investigator.

Kirk Peterson, MD, FACP, FACC, above right, is director of the Sulpizio Cardiovascular Center, Edith and William M. Perlman Professor of Clinical Cardiology and professor of medicine in the Division of Cardiology.

Amir Gamliel, PhD, is a postdoctoral research scientist in the Department of Medicine.

Read the research report in PLoS Genetics (open access article).