Protein May Be Key to Psoriasis and Wound Care

Psoriasis is an autoimmune disorder in which skin cells proliferate out of control. For some hard-to-heal wounds, the problem is just the opposite: Restorative skin cells don’t grow well or fast enough. In a paper published in the June 21, 2012 issue of Immunity, researchers at the University of California, San Diego School of Medicine describe a molecule that may lead to new treatments for both problems. … Read the full story from the UCSD Newsroom


Dr. Richard GalloThe principal investigator of this collaborative study is Richard L. Gallo, MD, PhD, professor of medicine and chief of the Division of Dermatology at UC San Diego.

The other Department of Medicine co-authors are Tissa Hata, MD, professor of medicine, Clinical Service Chief for Dermatology at the Perlman Ambulatory Care Center and Director of the UCSD Dermatology Clinical Trials Unit; Beda Mühleisen, MD; and Paul Kotol.

More information:

  • Read the article summary in Immunity.
  • Citation: Yuping Lai, Dongqing Li, Changwei Li, Beda Muehleisen, Katherine A. Radek, Hyun Jeong Park, Ziwei Jiang, Zhiheng Li, Hu Lei, Yanchun Quan, Tian Zhang, Yelin Wu, Paul Kotol, Shin Morizane, Tissa R. Hata, Keiji Iwatsuki, Ce Tang, Richard L. Gallo, The Antimicrobial Protein REG3A Regulates Keratinocyte Proliferation and Differentiation after Skin Injury, Immunity, Available online 21 June 2012, ISSN 1074-7613, 10.1016/j.immuni.2012.04.010.
  • Dr. Gallo’s laboratory website