UC San Diego Researchers Develop Efficient Model for Generating Human Stem Cells

Approach has potential to simplify generation of iPSCs for use in human stem cell therapies

Researchers at the University of California, San Diego School of Medicine report a simple, easily reproducible RNA-based method of generating human induced pluripotent stem cells (iPSCs) in the August 1 edition of Cell Stem Cell. Their approach has broad applicability for the successful production of iPSCs for use in human stem cell studies and eventual cell therapies. … Read the full story from the UCSD Newsroom


Four Department of Medicine researchers are coauthors of the study report in Cell Stem Cell:

Citation for the study report: Naohisa Yoshioka, Edwige Gros, Hai-Ri Li, Shantanu Kumar, Dekker C. Deacon, Cornelia Maron, Alysson R. Muotri, Neil C. Chi, Xiang-Dong Fu, Benjamin D. Yu, Steven F. Dowdy. Efficient Generation of Human iPSCs by a Synthetic Self-Replicative RNA. Cell Stem Cell – 1 August 2013 (Vol. 13, Issue 2, pp. 246-254)  |  Read the report