In First Moments of Infection, a Division and a Decision

UC San Diego scientists explain how and when T cells become effector or memory lymphocytes

Using technologies and computational modeling that trace the destiny of single cells, researchers at the University of California, San Diego School of Medicine describe for the first time the earliest stages of fate determination among white blood cells called T lymphocytes, providing new insights that may help drug developers create more effective, longer-lasting vaccines against microbial pathogens or cancer.

The findings are published in the March 2, 2014 online issue of Nature Immunology. … Read the full story from the UC San Diego News Center


Dr. John ChangStudy co-principal investigator John T. Chang, MD, PhD, is assistant professor of medicine in the Division of Gastroenterology.

Visit Dr. Chang’s Laboratory Website