Breast Cancer Drug Beats Superbug

Tamoxifen helps white blood cells clear multidrug-resistant bacteria in lab and mouse studies —

Researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences have found that the breast cancer drug tamoxifen gives white blood cells a boost, better enabling them to respond to, ensnare and kill bacteria in laboratory experiments. Tamoxifen treatment in mice also enhances clearance of the antibiotic-resistant bacterial pathogen MRSA and reduces mortality. …Read the full story from the UC San Diego Newsroom


Dr. John ChangFaculty coauthors of the study report include John T. Chang, MD, associate professor in the Division of Gastroenterology. His laboratory website is here.

Read the article abstract in Nature Communications. (Article full text, UC San Diego only)