Nation’s First Angioedema Treatment Center Is at UC San Diego

US Hereditary Angioedema Association and four corporate partners endow center to treat rare hereditary swelling disease —

It is rare for an “orphan” disease (typically a condition that affects fewer than 200,000 people nationwide) to have a specific center dedicated to providing treatment and research. And it is even more unusual for big pharmaceutical companies to invest in an endowment to fund this type of center. Fortunately, the US Hereditary Angioedema Association (HAEA), a nonprofit patient advocacy organization, along with four pharmaceutical companies—Shire Human Genetics Therapies Inc., ViroPharma Incorporated (which merged with Shire), Dyax Corp. and CSL Bering—pledged a total of $4.6 million to help make the US HAEA Angioedema Center at UC San Diego Health System a reality. A number of individuals, including those with the disease, also provided private support. … Read the full story from the UC San Diego News Center


Dr. Bruce Zuraw

Dr. Bruce Zuraw

Dr. Bruce Zuraw is director of the US HAEA Angioedema Center at UC San Diego Health System and inaugural recipient of the US HAEA Endowed Chair at UC San Diego. He is professor of medicine and chief of the Division of Rheumatology, Allergy & Immunology.

Dr. Marc Riedl

Dr. Marc Riedl

Marc Riedl, MD, MS, associate professor of medicine, is clinical director of the center.

 

New Cellular Pathway Triggering Allergic Asthma Response Identified

With molecular target found comes possibility of new therapies for millions of Americans —

Researchers at the University of California, San Diego School of Medicine, with collaborators in Korea and Scotland, have identified a novel signaling pathway critical to the immune response of cells associated with the initiation of allergic asthma. The discovery, they say, could point the way to new therapies that suppress the inflammatory allergic response, offering potential relief to millions of Americans with the chronic lung condition and potentially other allergic diseases.

The results are published in the January 19 online Early Edition of the Proceedings of the National Academy of Sciences. . … Read the full story from the UC San Diego Newsroom


Dr. Eyal Raz

Dr. Eyal Raz

Principal investigator of the study is Eyal Raz, MD, professor of medicine in the Division of Rheumatology, Allergy and Immunology, whose research focuses on the fundamentals of innate immunity.

First author of the report is Jihyung Lee, PhD, a postdoctoral fellow in the Raz lab.

Coauthors include David H. Broide, MB, ChB, professor of medicine and director of the division’s National Institute of Allergy and Infectious Diseases-funded T32 training program in molecular and cell biology of allergy; Paul Insel, MD, professor of pharmacology and medicine; Maripat Corr, MD, professor of medicine; project scientist Jongdae Lee, PhD; all in the Division of Rheumatology, Allergy and Immunology; and Nicholas Webster, PhD, professor of medicine and chief of the UC San Diego Division of Endocrinology and Metabolism.

View article abstract

Thomas Savides, MD, Named Chief Experience Officer for UC San Diego Health System

Thomas Savides, MD, has been named as the first Chief Experience Officer at UC San Diego Health System. In the newly created role, Savides will be responsible for the strategy, leadership and implementation of the plan to improve the total health care experience of patients, families, providers and staff. … Read the full story from the UC San Diego Newsroom

First Angioedema Treatment Center Opens at UC San Diego Health System

UC San Diego Health System in partnership with the U.S. Hereditary Angioedema Association (HAEA), a non-profit patient advocacy organization, has opened the nation’s first dedicated center for diagnosing and treating diverse forms of swelling, known collectively as angioedema.

The U.S. HAEA Angioedema Center at UC San Diego Health System will serve as an international referral center for people with all types of angioedema and will work closely with basic science laboratories at UC San Diego School of Medicine to better understand the condition and develop new treatments. … Read the full story from the UC San Diego Newsroom


Dr. Bruce Zuraw

Dr. Bruce Zuraw

Bruce Zuraw, MD, professor of medicine and chief of the Division of Rheumatology, Allergy and Immunology, is the U.S. HAEA Angioedema Center’s director and the inaugural recipient of the U.S. HAEA Endowed Chair at UC San Diego.  |  Dr. Zuraw’s clinical profile

Dr. Marc Riedl

Dr. Marc Riedl

Marc Riedl, MD, MS, associate professor of medicine, is the Center’s clinical director.  |  Dr, Riedl’s clinical profile

 

San Diego’s 2014 Top Doctors List Includes 44 from Department of Medicine

Forty-four physicians from the Department of Medicine are among over 100 UC San Diego Health System doctors named to the 2014 San Diego Top Doctors list. See the list for UC San Diego Health System.

Not present on that list are two additional internal medicine physicians who practice at the VA San Diego Healthcare System: Charles Goldberg, MD, and Simerjot Jassal, MD. Dr. Jassal directs the Internal Medicine Residency Program.

The Top Doctors list comes from the annual “Physicians of Exceptional Excellence” survey from the San Diego County Medical Society and San Diego Magazine.

Read the UC San Diego Health System press release

Pepper and Halt: Spicy Chemical May Inhibit Gut Tumors

Researchers at the University of California, San Diego School of Medicine report that dietary capsaicin – the active ingredient in chili peppers – produces chronic activation of a receptor on cells lining the intestines of mice, triggering a reaction that ultimately reduces the risk of colorectal tumors.

The findings are published in the August 1, 2014 issue of The Journal of Clinical InvestigationRead the full story from the UCSD Newsroom


Eyal Raz, MD

Eyal Raz, MD

Senior author of the study is Eyal Raz, MD, professor of medicine in the Division of Rheumatology, Allergy and Immunology.

Dr. Lars Eckmann

Lars Eckmann, MD

Department of Medicine faculty coauthors include Lars Eckmann, MD, right, professor of medicine, and Hui Dong, MD, PhD, associate professor, both in the Division of Gastroenterology; and Maripat Corr, MD, professor of medicine in the Division of Rheumatology, Allergy & Immunology.

Maripat Corr, MD

Maripat Corr, MD

Hannah Carter Receives NIH Early Independence Award

CTRI Helps Launch Career of Bioengineer Hannah Carter

November 22, 2013 – With support from UC San Diego’s Clinical and Translational Research Institute (CTRI), bioengineer Hannah Carter, PhD, received the highly prestigious NIH Early Independence Award and recently began began her transition to a junior faculty position at UC San Diego.

Presently she is acquiring a research team and computational resources to delve into her project: Network approaches to identify cancer drivers from high-dimensional tumor data. … Read the full story from CTRI News & Events


Hannah Carter, PhDHannah Carter, PhD, is assistant professor of medicine in the Division of Medical Genetics. Her project is Network Approaches to Identify Cancer Drivers from High-Dimensional Tumor Data.

She is now recruiting postdoctoral fellows for her project, which is funded for five years.

Carter Laboratory website

 

UC San Diego Health System Retains #1 Ranking

US News & World Report Cites Region’s Only Academic Health System Among Nation’s Best 

UC San Diego Health System remains among the nation’s best, according to the U.S. News & World Report’s 2014-15 issue of “America’s Best Hospitals,” released this week. The magazine’s widely cited findings again placed UC San Diego Health System first in the San Diego metropolitan area and fifth in California, with national rankings in 11 specialties, up from 10 last year. This is comparable to the country’s most prestigious health care institutions.  Read the full story from the UCSD Newsroom


Sulpizio Cardiovascular CenterUC San Diego Health System is nationally ranked in eleven medical specialties, including seven in the Department of Medicine:  Cancer, Cardiology, Endocrinology & Diabetes, Gastroenterology, Geriatrics, Nephrology, Pulmonology and Rheumatology.

Molecular Tumor Board Helps in Advanced Cancer Cases

With accelerating development of personalized cancer treatments matched to a patient’s DNA sequencing, proponents say frontline physicians increasingly need help to maneuver through the complex genomic landscape to find the most effective, individualized therapy.

In a paper published in the May 5 online issue of The Oncologist, researchers at the University of California, San Diego School of Medicine and Moores Cancer Center detail their experience evaluating 34 patients between December 2012 and June 2013 using a molecular tumor board – a new type of advisory group comprised of multidisciplinary experts, including those in the fields of tumor genetics, basic science and bioinformatics. … Read the full story from the UC San Diego Newsroom

UC San Diego Health System Excels in Patient Safety

Awarded an “A” in Spring 2014 Hospital Safety Score

Designed to rate how well hospitals protect patients from accidents, errors, injuries and infections, the latest Hospital Safety Score honored UC San Diego Health System with an “A” – its top grade in patient safety. The Hospital Safety Score is compiled under the guidance of the nation’s leading experts on patient safety and is administered by The Leapfrog Group (Leapfrog), an independent industry watchdog. …Read the full story from the UC San Diego Newsroom