A protein used by embryo cells during early development, and recently found in many different types of cancer, apparently serves as a switch regulating the spread of cancer, known as metastasis, report researchers at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center in the June 15, 2013 issue of the journal Cancer Research. … Read the full story from the UCSD Newsroom
Thomas Kipps, MD, PhD, Evelyn and Edwin Tasch Chair in Cancer Research, is principal investigator of the study reported in Cancer Research.
All study coauthors are affiliated with the Department of Medicine and the Moores Cancer Center.
Citation for the published study: Cui B, Zhang S, Chen L, Yu J, Widhopf GF II, Fecteau J-F, Rassenti LZ, and Kipps TJ. Targeting ROR1 Inhibits Epithelial–Mesenchymal Transition and Metastasis. doi: 10.1158/0008-5472.CAN-12-3832 Cancer Res June 15, 2013 73; 3649 | Read the abstract