Photo of Dr. W. Cameron McGuire MD

W. Cameron McGuire, MD

Pulmonary, Critical Care & Sleep MedicineUC San Diego Department of Medicine


Dr. McGuire was born in Chicago, but raised in Baltimore, MD. In college he became fascinated by the history of science and medicine and wrote his history thesis on the sociology of Charles Darwin’s concept of natural selection. Since college he has followed a circuitous path with stops at: the NIH doing research on cardiac myocyte survival and vascular smooth muscle cell migration, the University of Chicago doing research on DNA repair following exposure to ionizing radiation or cisplatinum, Tulane University doing research on the role of endothelin signaling in intrarenal renin production, and University of Colorado doing research on heart failure medication adherence and nonpharmacologic interventions for the acute respiratory distress syndrome. Ultimately, he hopes to pursue a research career in clinical outcomes or health services in a pulmonary subspecialty such as lung transplant, interstitial lung disease, or pulmonary hypertension. His interests include: cooking, travel, jazz, history, classic movies, and cocktails to name a few.

Education & Training

  • 2003-2007: Trinity College (Hartford, CT), B.S. – Biology; BA – History
  • 2009-2010: Loyola University Chicago, M.A. – Medical Sciences
  • 2011-2015: Tulane School of Public Health and Tropical Medicine, M.P.H. – Epidemiology
  • 2011-2015: Tulane University School of Medicine, M.D.
  • 2015-2018: University of Colorado School of Medicine, Internal Medicine Resident
  • 2018-2019: University of Colorado School of Medicine, Chief Resident
  • 2019-2022: University of California San Diego, PCCM Fellow


Key Publications

1) Matlock DD, McGuire WC, Magid M, Allen LA. Decision making in advanced heart
failure: bench, bedside, practice, and policy. Heart Failure Reviews 22(5): 559-564, September 2017.

2) McGuire C, Liu L, Prieto M. The role of endothelin-1 in collecting duct renin synthesis
and secretion. Journal of Investigative Medicine 61(2): 449, February 2013. (Abstract)

3) Budke B, Logan HL, Kalin JH, Zelivianskaia AS, Cameron McGuire W, Miller LL,
Stark JM, Kozikowski AP, Bishop DK, Connell PP. RI-1: A chemical inhibitor of RAD51 that disrupts homologous recombination in human cells. Nucleic Acids Research 40(15): 7347-57, August 1, 2012.

4) Renn CL, Lessans S, McGuire WC, Smith B, Traub RJ, Dorsey SG. Brain-derived
neurotrophic factor modulates antiretroviral-induced mechanical allodynia in the mouse. Journal of Neuroscience Research 89(10): 1551-65, June 6, 2011.