Researchers at the University of California, San Diego School of Medicine and colleagues report that the herpes simplex virus type-1 (HSV-1), which affects an estimated 50 to 80 percent of all American adults, exploits an immune system receptor to boost its infectivity and ability to cause disease. … Read the full story from the UCSD Newsroom
Richard L. Gallo, MD, PhD, left, is principal investigator of the study, which is reported in the online-only journal Nature Communications.
Gallo is professor of medicine and chief of the Division of Dermatology.
Citation for the study report: Daniel T. MacLeod, Teruaki Nakatsuji, Kenshi Yamasaki, Lester Kobzik & Richard L. Gallo. HSV-1 exploits the innate immune scavenger receptor MARCO to enhance epithelial adsorption and infection. Nature Communications 4, Article number: 1963. doi:10.1038/ncomms2963. Published 06 June 2013. | Abstract