Applying Machine-to-Machine (M2M) Technology to Verify Compliance with Tuberculosis Treatment Regimen
The honor comes from Connected World magazine, which presents the M2M Pioneer awards to a small number of outstanding innovators in machine-to-machine technology each year.
The VDOT program uses smartphone video to verify that tuberculosis patients comply with the painstaking six-month regimen of antibiotics required for a cure. Incomplete treatment fails to cure the TB and raises the risk that antibiotic-resistant strains of TB will develop.
Richard Garfein, PhD, MPH, an infectious disease epidemiologist, is professor of medicine in the Division of Global Public Health. The inspiration for the VDOT program came to him as he watched his children use smartphones to send videos to their friends.
Kevin Patrick, MD, MS, is director of the Center for Wireless and Population Health Systems at the Qualcomm Institute (the San Diego division of Calit2) and professor of family and preventive medicine in the Division of Preventive Medicine.
In their NIH-funded pilot study in San Diego and Tijuana in 2011-2012, Garfein and Patrick demonstrated that the VDOT program was an effective tool for ensuring that patients adhered to their treatment regimens.
They also showed that VDOT could reduce costs for the local public health agency; in the pilot study, the San Diego County Health and Human Services Agency. The agency’s only previous option had been to send health workers to patients’ homes to watch them take their medications.
Garfein and Patrick reported their results in an mHealth Summit Meeting abstract published in the Journal of Mobile Technology in Medicine.
Now, Garfein and colleagues are working on implementing the program on a larger scale through a public/private partnership with the Verizon Foundation, which provides funding and in-kind assistance.
The Garfein-Patrick team included other faculty and staff of the Global Public Health division and a number of specialists from the Qualcomm Institute.
“Congratulations to them both, and to Ramesh Rao and their team from the Qualcomm Institute, for this fantastic achievement and excellent teamwork,” said Steffanie Strathdee, PhD, Harold Simon Professor, Associate Dean of Global Health Sciences and chief of the Division of Global Public Health.
Ramesh Rao, PhD, director of the San Diego division of the Qualcomm Institute, holds the QUALCOMM Endowed Chair in Telecommunications and Information Technology. He is professor of electrical and computer engineering in the Jacobs School of Engineering at UC San Diego.
Said Garfein, “Working with Kevin and collaborating with the expert programmers at the Qualcomm Institute has been one of the highlights of my academic career.
“Although they are not included in the article because of the magazine’s information technology focus, we wouldn’t have been as successful if it weren’t for all the hard work by Jazmine Cuevas-Mota, Kelly Collins, and Fatima Muñoz in the Division of Global Public Health, and the dedicated employees of the San Diego County TB Control Program led by Dr. Kathleen Moser,” he said.
In the Division of Global Public Health, Cuevas-Mota is a project coordinator for Garfein, Collins is an assistant project coordinator and Muñoz is a postdoctoral fellow on the project.
“This has been a terrific project and it’s been a true pleasure to work with Richard and his team on it,” said Patrick.
“With a bit of luck, this could have world-wide impact on the health of the public. When all is said and done, this is why we are in this game.”
“This is very exciting and well deserved,” said Susan Taylor, PhD, UC San Diego professor of chemistry and biochemistry and pharmacology. She is a Howard Hughes Medical Institute investigator in biophysics and structural biology.
“It has been so much fun for me to watch these amazing things unfold and to realize how much we can achieve by working together and building bridges across the boundaries of our campus. This is much of what makes UCSD so special.“
UC San Diego Health Sciences Video: VDOT Technology Eases Monitoring for Patients with Tuberculosis
- VCP-DOT: Video Cell Phone – Directly Observed Therapy for Tuberculosis – pilot project description
- mHealth Summit Meeting abstract in the Journal of Mobile Technology in Medicine
- UC San Diego and Verizon Team to Improve Tuberculosis Care – UC San Diego news story about the next step in VDOT development at UC San Diego