UC San Diego Researchers Develop Efficient Model for Generating Human Stem Cells

Approach has potential to simplify generation of iPSCs for use in human stem cell therapies

Researchers at the University of California, San Diego School of Medicine report a simple, easily reproducible RNA-based method of generating human induced pluripotent stem cells (iPSCs) in the August 1 edition of Cell Stem Cell. Their approach has broad applicability for the successful production of iPSCs for use in human stem cell studies and eventual cell therapies. … Read the full story from the UCSD Newsroom


Four Department of Medicine researchers are coauthors of the study report in Cell Stem Cell:

Citation for the study report: Naohisa Yoshioka, Edwige Gros, Hai-Ri Li, Shantanu Kumar, Dekker C. Deacon, Cornelia Maron, Alysson R. Muotri, Neil C. Chi, Xiang-Dong Fu, Benjamin D. Yu, Steven F. Dowdy. Efficient Generation of Human iPSCs by a Synthetic Self-Replicative RNA. Cell Stem Cell – 1 August 2013 (Vol. 13, Issue 2, pp. 246-254)  |  Read the report

Drs. Catriona Jamieson and Benjamin Yu Awarded CIRM New Faculty Grants

Drs. Catriona Jamieson and Benjamin Yu are among four UCSD researchers to receive New Faculty II grants from the California Institute for Regenerative Medicine (CIRM).

Catriona Jamieson, M.D., Ph.D., is Assistant Professor of Medicine in the Division of Hematology-Oncology and Director of Stem Cell Research at the Moores UCSD Cancer Center.

Dr. Jamieson investigates stem-cell treatments for myeloproliferative diseases (MPD), with the goal of preventing MPD from developing into leukemia.  |  Read the public abstract for Dr. Jamieson’s research project

Benjamin D. Yu, M.D., Ph.D., is Assistant Professor of Medicine in the Division of Dermatology.

The CIRM grant will support Dr. Yu’s work to uncover the mechanisms that regulate the proliferation of pre-existing adult stem cells in the body.  |  Read the public abstract for Dr. Yu’s research project

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