Creating Clinical Bioengineers

New class teaches undergrads to use engineering-based solutions to bridge gap between engineering and medicine —

A group of UC San Diego bioengineering students huddle around a computer screen as colored images of blood being pumped through a heart flash across the screen. The students are observing as a physician annotates an MRI of a patient’s heart and recommend treatment.

“It looks like there is fat here where there shouldn’t be,” says the physician as he pointed to a spot on the screen. “See how this part of the heart isn’t contracting?” … Read the Full Story from the UC San Diego Newsroom


The Division of Cardiology in the Department of Medicine is one of the rotation sites in the Clinical Bioengineering class.

No. 1 From the Start

UC San Diego Bioengineering ranked first by National Research Council since founding 50 years ago —

Bioengineers at UC San Diego have helped us understand why atherosclerosis develops and how it is impacted by blood flow. They have pioneered the development of very thin, small and flexible sensors that stick to the skin and monitor vital signs, such as the brain activity of a newborn. They also developed injectable hydrogels that can help muscle tissues heal after a heart attack.

Researchers celebrated their achievements over the past five decades and looked to the future during a three-day 50th anniversary celebration May 19 to 21. … Read the Full Story from the UC San Diego Newsroom


Shu Chien, PhD

Shu Chien, PhD

The founding chair of the UC San Diego Department of Bioengineering is Shu Chien, PhD, Distinguished Professor of Medicine in the Division of Physiology and Professor of Bioengineering. He is founding director of the UC San Diego Institute of Engineering in Medicine.

Dr. Chien is an elected Fellow of the National Academy of Inventors and the American Association for the Advancement of Science, among many honorific societies, and he received the Franklin Institute Award in November 2015.

Distinguished Professor Shu Chien Elected Fellow of National Academy of Inventors

December 15, 2015

Two researchers at the University of California, San Diego, have been named fellows of the National Academy of Inventors.

Shu Chien, Distinguished Professor of Bioengineering and Medicine, and Michael Sailor, Distinguished Professor of Chemistry and Biochemistry, were among 168 new fellows announced by the academy today.. … Read the full story from the UC San Diego Newsroom


Shu Chien, MD, PhD

Shu Chien, MD, PhD. Photo courtesy of Jacobs School of Engineering/UC San Diego.

Shu Chien, MD, PhD, is a world-renowned researcher and inventor who has conducted pioneering investigations in atherosclerosis and hypertension. His work has brought about significant advances in the diagnosis and treatment of cardiovascular disease.

Dr. Chien is founding chair of the UC San Diego Department of Bioengineering and director of the Institute of Engineering in Medicine. In the Department of Medicine, he is Distinguished Professor of Medicine in the Division of Physiology.

Earlier in 2015, Dr. Chen was selected to receive the prestigious Franklin Institute Award and was elected a fellow of the American Association for the Advancement of Science.

Professor Shu Chien Receives Prestigious Franklin Institute Award

November 16, 2015

Philadelphia, Nov. 12, 2015 – Shu Chien, founding chair of the Department of Bioengineering at the University of California, where is he currently a professor and director of the Institute of Engineering in Medicine, has received the prestigious Franklin Institute Award.

The award is conferred by the Philadelphia-based Franklin Institute. It has gone in previous years to an extraordinary list of great men and women who have significantly improved our world with their pioneering innovations, including Thomas Edison, Marie Curie, Stephen Hawking, Jacques Cousteau, and more recently Jane Goodall, Dean Kamen and Bill Gates. … Read the full press release from the Jacobs School of Engineering


Shu Chien, MD, PhD

Shu Chien, MD, PhD. Photo courtesy of Jacobs School of Engineering/UC San Diego.

In addition to his leadership roles in the Department of Bioengineering and the Institute of Engineering in MedicineShu Chien, MD, PhD, is a Professor of Medicine in the Division of Physiology.

In a recent major development in his scientific explorations, Dr. Chien is one of four principal investigators in the organizational hub of the $30 million 4D Nucleome Research Centers and Organizational Hub grant the National Institutes of Health awarded to UC San Diego in October.

The goal of the project is to determine how DNA is arranged within the cell’s nucleus in four dimensions (three-dimensional space plus time) and how changes in that nuclear organization affect human health and disease.

More information about Dr. Chien and his work:

Dr. Trey Ideker Named AAAS Fellow

Trey Ideker, PhD

Trey Ideker, PhD

Trey Ideker, PhD, professor of medicine in the Division of Medical Genetics and professor of bioengineering, is one of three UC San Diego faculty members to be named Fellow of the American Association for the Advancement of Science (AAAS) this year. …Read the full story from the UC San Diego Newsroom.

 

Hannah Carter Receives NIH Early Independence Award

CTRI Helps Launch Career of Bioengineer Hannah Carter

November 22, 2013 – With support from UC San Diego’s Clinical and Translational Research Institute (CTRI), bioengineer Hannah Carter, PhD, received the highly prestigious NIH Early Independence Award and recently began began her transition to a junior faculty position at UC San Diego.

Presently she is acquiring a research team and computational resources to delve into her project: Network approaches to identify cancer drivers from high-dimensional tumor data. … Read the full story from CTRI News & Events


Hannah Carter, PhDHannah Carter, PhD, is assistant professor of medicine in the Division of Medical Genetics. Her project is Network Approaches to Identify Cancer Drivers from High-Dimensional Tumor Data.

She is now recruiting postdoctoral fellows for her project, which is funded for five years.

Carter Laboratory website

 

In Epigenomics, Location is Everything

Researchers exploit gene position to test “histone code”

In a novel use of gene knockout technology, researchers at the University of California, San Diego School of Medicine tested the same gene inserted into 90 different locations in a yeast chromosome – and discovered that while the inserted gene never altered its surrounding chromatin landscape, differences in that immediate landscape measurably affected gene activity. … Read the full story from the UCSD Newsroom


Trey Ideker, PhD

Led by Trey Ideker, PhD, researchers in the UCSD departments of bioengineering, biological sciences, and medicine collaborated in the study, which was published online this week in Cell Reports.

Ideker is professor of bioengineering and medicine and chief of the Division of Medical Genetics in the Department of Medicine.

The study investigators include Lorraine Pillus, PhD, professor and chair of the Section of Molecular Biology in the Division of Biological Sciences at UCSD, whose laboratory focuses on investigating chromosomal and chromatin effects on the expression of genes.

Citation for the study report: Chen M, Licon K, Otsuka R, Pillus L, and Ideker T. (2013) Decoupling Epigenetic and Genetic Effects through Systematic Analysis of Gene Position. 10.1016/j.celrep.2012.12.003   Read the article abstract.

BPA’s Real Threat May Be After It Has Metabolized

Chemical found in many plastics linked to multiple health threats

Bisphenol A or BPA is a synthetic chemical widely used in the making of plastic products ranging from bottles and food can linings to toys and water supply lines. When these plastics degrade, BPA is released into the environment and routinely ingested… Read the full story from the UCSD Newsroom


Department of Medicine researcher Michael E. Baker, PhD, teamed with UCSD Department of Bioengineering graduate student Charlie Chandsawangbhuwana in the study. Dr. Baker is a research scientist in the Division of Nephrology/Hypertension.

Injectable Gel Could Repair Tissue Damaged by Heart Attack

University of California, San Diego researchers have developed a new injectable hydrogel that could be an effective and safe treatment for tissue damage caused by heart attacks. The study by Karen Christman and colleagues appears in the Feb. 21 issue of the Journal of the American College of Cardiology … Read the full story from the UCSD Newsroom


The UCSD research team includes Dr. Anthony DeMaria. Anthony N. DeMaria, MD, founding director of the Sulpizio Cardiovascular Center, holds the Judith and Jack White Chair in Cardiology.  |  Read the research report