Old drug used for sleeping sickness may point to new treatment in humans
In a further test of a novel theory that suggests autism is the consequence of abnormal cell communication, researchers at the University of California, San Diego School of Medicine report that an almost century-old drug approved for treating sleeping sickness also restores normal cellular signaling in a mouse model of autism, reversing symptoms of the neurological disorder in animals that were the human biological age equivalent of 30 years old. … Read the full story from the UC San Diego Newsroom
Infectious disease specialist Dr. Joseph Vinetz and colleagues have discovered a new species of bacteria that may be a major cause of a potentially fatal tropical disease.
The disease, leptospirosis, is transmitted from animals to humans. Severe forms of leptospirosis have high fatality rates.
Joseph Vinetz, M.D., is Professor of Medicine in the Division of Infectious Diseases. In the study, he collaborated with researchers at other North American centers and the Universidad Peruana Cayetano Heredia in Lima, Peru.
The study was published in the April 1 issue of Neglected Tropical Diseases:
Matthias MA, Ricaldi JN, Cespedes M, … and Vinetz, JM. Human Leptospirosis Caused by a New, Antigenically Unique Leptospira Associated with a Rattus Species Reservoir in the Peruvian Amazon. PLoS Negl Trop Dis. 2008 April; 2(4): e213. Published online 2008 April 2. doi: 10.1371/journal.pntd.0000213. Read the report