Dr. Christopher K. Glass Among Three UC San Diego Researchers Elected to National Academy of Medicine

Ferrara, Glass and Malinow join premier advisory group on national medical and health issues —

The National Academy of Medicine (NAM) announced today the election of three new members from University of California, San Diego School of Medicine: Napoleone Ferrara, MD; Christopher K. Glass, MD, PhD; and Roberto Malinow, MD, PhD. Election to NAM is considered among the highest honors in the fields of health and medicine. …Read the full story from the UC San Diego Newsroom


Christopher K. Glass, MD, PhDChristopher K. Glass, MD, PhD, is Professor of Cellular and Molecular Medicine and Professor of Medicine in the Division of Endocrinology and Metabolism.

Glass Lab Website

Christopher K. Glass and Clifford P. Kubiak Elected to the American Academy of Arts and Sciences

Two UC San Diego faculty members have been elected to the American Academy of Arts and Sciences, one of the nation’s most prestigious honorary societies, which includes accomplished leaders from academe, business, public affairs, the humanities and the arts.

Christopher K. Glass, a professor of medicine and of cellular and molecular medicine, and Clifford P. Kubiak, a distinguished professor of chemistry and biochemistry, join the 2014 class of academy members … Read the full story from the UC San Diego Newsroom

Plasticity of Hormonal Response Permits Rapid Gene Expression Reprogramming

Gene expression reprogramming may allow cancer cell growth as well as normal differentiation

Gene expression is the process of converting the genetic information encoded in DNA into a final gene product such as a protein or any of several types of RNA. Scientists have long thought that the gene programs regulated by different physiological processes throughout the body are robustly pre-determined and relatively fixed for every specialized cell. But a new study by researchers from the University of California, San Diego School of Medicine reveals the unsuspected plasticity of some of these gene expression programs. … Read the full story from the UCSD Newsroom

M. Geoffrey Rosenfeld, MD

Co-principal investigator of the study is Dr. M. Geoffrey Rosenfeld (pictured at left). M. Geoffrey Rosenfeld, MD, is Professor of Medicine in the Division of Endocrinology and Metabolism and Howard Hughes Medical Institute investigator.

Department of Medicine coauthor Christopher K. Glass, MD, PhD, is Professor of Medicine in the Division of Endocrinology and Metabolism and Professor of Cellular and Molecular Medicine.

Read the published study in Nature (free full text).

Researchers Describe First Functioning “Lipidome” of Mouse Macrophage

For the first time, scientists have described not only the identities and quantities of fat species in a living mammalian cell – in this case, a mouse macrophage or white blood cell – but they also report how these lipids react and change over time … Read the full story from the UCSD Newsroom

Dr. Gary Hardiman

Three coauthors of the research report in the Journal of Biological Chemistry are members of the Division of Endocrinology and Metabolism in the Department of Medicine: Oswald Quehenberger, Ph.D., Professor of Medicine; Christopher K. Glass, M.D., Ph.D., Professor of Medicine and Professor of Cellular and Molecular Medicine; and Gary Hardiman, Ph.D. (pictured above), Associate Professor of Medicine and Director of the Biomedical Genomics Microarray Facility.

Cholesterol-Lowering Statins Boost Bacteria-Killing Cells

Widely prescribed for their cholesterol-lowering properties, recent clinical research indicates that statins can produce a second, significant health benefit: lowering the risk of severe bacterial infections such as pneumonia and sepsis… Read the full story from the UCSD Newsroom

Christopher K. Glass, M.D., Ph.D.

Department of Medicine coauthors on the published paper are Anna L. Kogen, Ph.D., Richard Gallo, M.D., Ph.D., Professor of Medicine and Pediatrics and Chief of the Division of Dermatology; and corresponding author Christopher K. Glass, M.D., Ph.D. (pictured above), Professor of Medicine in the Division of Endocrinology and Metabolism and Professor of Cellular and Molecular Medicine.

Read the published study (PDF).

Macrophage Protein Has Major Role in Inflammation

Researchers at the University of California, San Diego School of Medicine have discovered that a multi-tasking protein called FoxO1 has another important but previously unknown function: It directly interacts with macrophages, promoting an inflammatory response that can lead to insulin resistance and diabetes. Contrarily, it also generates a negative feedback loop that can limit damage from excessive inflammation… Read the full story from the UCSD Newsroom

Dr. Jerrold Olefsky

The researchers are Jerrold M. Olefsky, M.D., and coworkers.  Dr. Olefsky is Professor of Medicine in the Division of Endocrinology and Metabolism and Associate Dean for Scientific Affairs, UC San Diego Health Sciences.

Read the published study (full text).

Dr. Christopher Glass and Colleagues Awarded $38 Million to Continue Lipid Mapping Project

Christopher K. GlassDr. Christopher K. Glass and colleagues at UCSD have received a renewal award of nearly $38 million to lead the Lipid Metabolites and Pathways Strategy (MAPS) Project for another five years.

Begun in 2003, the Lipid MAPS project is a 16-center consortium study of the structure and function of lipids. Lipids play a role in many major disorders including Alzheimer’s disease, arthritis, cancer, diabetes, heart disease, and stroke.

Christopher K. Glass, M.D., Ph.D., is Professor of Medicine in the Division of Endocrinology and Metabolism and Professor of Cellular and Molecular Medicine at UCSD. He is director of the LIPID MAPS Macrophage Biology Core.

Principal investigator of the Lipid MAPS consortium is Edward Dennis, Ph.D., Distinguished Professor of Pharmacology and Chemistry and Biochemistry at UCSD. The project is funded by the National Institute of General Medical Sciences.


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To Prevent Heart Disease, Treat High Cholesterol Early in life, Dr. Daniel Steinberg and colleagues say

Early childhood is the time to start lowering cholesterol to prevent heart disease, according to Dr. Daniel Steinberg and colleagues at UCSD.

Daniel Steinberg, M.D., Ph.D., is Emeritus Professor of Medicine in the Division of Endocrinology & Metabolism. He is renowned for his groundbreaking research in cholesterol and atherosclerosis.

Read the full story from UC San Diego
Health Sciences Communications

His colleagues and co-authors, Christopher K. Glass, M.D., Ph.D., and Joseph Witztum, M.D., are both professors of medicine. All three researchers are members of the Division of Endocrinology & Metabolism.

Their analysis and recommendations are published in the August 5 issue of the journal Circulation.

Citation for the article:  Steinberg, Daniel MD, PhD; Glass, Christopher K. MD, PhD; Witztum, Joseph L. MD. Evidence Mandating Earlier and More Aggressive Treatment of Hypercholesterolemia. Circulation 2008 August 5;118(6):172-177. – |  Read the article (PDF)

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