$52M NIH Grant Advances Clinical and Translational Research at UC San Diego

Federal funding will help further on-going efforts to translate discoveries to clinic —

The Clinical and Translational Research Institute (CTRI) at University of California, San Diego has received a five-year Clinical and Translational Science Award (CTSA) for approximately $52 million from the National Center for Advancing Translational Science, part of the National Institutes of Health. … Read the full story from the UC San Diego News Center

Daniel T. O’Connor Memorial Award Established to Support CTRI Pilot Project

The UC San Diego Clinical and Translational Research Institute (CTRI) has announced the Daniel T. O’Connor Memorial Award, which will add funding to support the top 2015 CTRI project recipient, Julie Bykowski, MD. The award was established by Dr. O’Connor’s widow, Kellie Evans-O’Connor.  Read the story in the UC San Diego Clinical and Translational News & Announcements

Live Long and Measure: Quest to Create Real-World Tricorder

XPRIZE teams will test Star Trek-inspired medical devices at UC San Diego —

Seeking to boldly go where medical science has not gone before, the Clinical and Translational Research Institute (CTRI) at the University of California, San Diego has been named the official testing site for the $10 million Qualcomm Tricorder XPRIZE, a global competition sponsored by the Qualcomm Foundation to develop a consumer-friendly, mobile device capable of diagnosing and interpreting 15 physiological conditions and capturing vital health metrics.

The XPRIZE competition is inspired by the tricorder medical device that debuted in the original 1966 Star Trek TV show and was frequently featured in subsequent series and movies. …Read the full story from the UC San Diego Newsroom


Dr. Gary FiresteinGary S. Firestein, MD, is director of the CTRI and dean and associate vice chancellor of translational medicine at UC San Diego.

He is professor of medicine in the Division of Rheumatology, Allergy and Immunology and served as division chief from 1998 until he stepped down in 2010 to focus on his growing responsibilities as dean of translational medicine and director of the CTRI for UC San Diego Health Sciences.

Hannah Carter Receives NIH Early Independence Award

CTRI Helps Launch Career of Bioengineer Hannah Carter

November 22, 2013 – With support from UC San Diego’s Clinical and Translational Research Institute (CTRI), bioengineer Hannah Carter, PhD, received the highly prestigious NIH Early Independence Award and recently began began her transition to a junior faculty position at UC San Diego.

Presently she is acquiring a research team and computational resources to delve into her project: Network approaches to identify cancer drivers from high-dimensional tumor data. … Read the full story from CTRI News & Events


Hannah Carter, PhDHannah Carter, PhD, is assistant professor of medicine in the Division of Medical Genetics. Her project is Network Approaches to Identify Cancer Drivers from High-Dimensional Tumor Data.

She is now recruiting postdoctoral fellows for her project, which is funded for five years.

Carter Laboratory website

 

University of California Launches its First Tool for Data Sharing Among Medical Centers with UC Research eXchange

Announcement for UC Investigators

Gary S. Firestein, MD
Chair, University of California Biomedical Research
Acceleration, Integration and Development (UCBRAID)
Professor of Medicine
Dean and Associate Vice Chancellor, Translational Medicine
Director, Clinical and Translational Research Institute
UC San Diego

Dr. Gary Firestein

Dr. Gary Firestein, UC BRAID Chair

The University of California Biomedical Research Acceleration, Integration and Development (UC BRAID; ucbraid.org) is pleased to announce the launch of the UC Research eXchange (UC ReX) and the UC ReX Data Explorer tool. This system enables exploration of a combined population of over 12 million patients from medical center databases at UC Los Angeles, UC Irvine, UC Davis, UC San Diego, and UC San Francisco.

UC ReX Data Explorer gives researchers and quality specialists access to cohort counts derived from de-identified clinical data collected at the point of care to improve medical care and advance research.

UC ReX was initiated by UC BRAID in 2011 with a 5-year grant of $5 million from the UC Office of the President (UCOP) and developed through a collaboration of the medical campuses and their Chief Information Officers and CTSAs.

An important part of UC BRAID’s mission is to improve UC collaborative research opportunities. UC ReX is a great example of how UC BRAID facilitates integration of research programs, clinical informatics, technology, and resources across University of California campuses.

To start exploring UC ReX with Data Explorer, please go to ucrex.org for more information.  |  See UC ReX Flier

Access UC-ReX via UC San Diego Clinical and Translational Research Institute

 

UC Medical Campus Consortium Named Designated Center to Translate Innovations into Improved Health

A consortium of the five University of California medical campuses at UC San Diego, UC Davis, UC Irvine, UCLA and UC San Francisco has been designated a Center for Accelerated Innovations by the National Heart, Lung and Blood Institute (NHLBI). The designation, among the first of its kind from NHLBI, recognizes the University of California’s potential to translate its leading-edge discoveries into innovative products that benefit patients. … Read the full story from the UCSD Newsroom


Dr. Gary FiresteinGary S. Firestein, MD, chair of the UC BRAID consortium that will oversee the new UC Center for Accelerated Innovations, is dean and associate vice chancellor of translational medicine at UC San Diego Health Sciences

He led UC San Diego’s successful effort to win a Clinical and Translational Science Award in 2010 and is the founding director of the UC San Diego Clinical and Translational Research Institute.

Firestein is professor of medicine and former chief of the Division of Rheumatology, Allergy & Immunology at UC San Diego. He served as division chief from 1998 until he stepped down in 2010 to devote full time to his activities as dean of translational medicine.

In 2011, philanthropists Lisa and Steve Altman made a major gift to the planned Clinical and Translational Research building on the La Jolla campus of UC San Diego Health System. Construction started in early 2013 and the building, named the Altman Clinical and Translational Research Institute, is scheduled to open in 2016.

UC San Diego Health System Video: The Altman Clinical and Translational Research Institute

More Information:

UCSD Health Sciences Partners with Pfizer to Speed Drug Delivery

Research agreement could represent more than $50 million over five years for development of new therapies to benefit major medical needs

In an innovative collaboration designed to speed the process of drug discovery, Pfizer, Inc. and the University of California, San Diego Health Sciences announced today that UC San Diego has joined the ranks of other top-tier life science research institutions across the country as part of Pfizer’s Centers for Therapeutic Innovation (CTI)…. Read the full story from the UCSD Newsroom

Dr. Greg Maynard: Two New Leadership Roles in Hospital Quality Improvement

Directing QI Initiatives for UC San Diego and the Society of Hospital Medicine


Dr. Greg Maynard Accepting new leadership positions in hospital quality improvement with UC San Diego and the Society of Hospital Medicine (SHM), Dr. Greg Maynard has stepped down as Hospital Medicine division chief effective July 1.

He will direct the UC San Diego Center for Innovation and Improvement Science (CIIS) and serve as Senior Vice President of the Society of Hospital Medicine’s new Center for Healthcare Improvement and Innovation (CHII).  |  Read the SHM press release >

“I’m excited about the opportunities for collaboration, improvement, and innovation afforded by each of these positions, as well as the potential synergy between them,” said Maynard.

A member of the UC San Diego Department of Medicine faculty since 2003, Maynard was the founding chief of the Division of Hospital Medicine when it was established in 2005.

“As division chief, Greg Maynard has developed one of the most respected and effective hospitalist programs in the country,” said Department of Medicine Interim Chair Wolfgang H. Dillmann, MD.

“I have no doubt that UC San Diego Health System and the Society of Hospital Medicine will make important advances in hospital quality and patient safety through his leadership.”

DrGregSeymannLongtime UC San Diego hospitalist Gregory B. Seymann, MD, SFHM, Health Sciences Clinical Professor, is the new Hospital Medicine division chief. For the past year, he has served as associate division chief with Dr. Bryan Huang.

“The Division of Hospital Medicine has benefited greatly from Dr. Maynard’s leadership.” Seymann said. “I will work hard during this transition to maintain the excellent patient care, teaching, and systems improvement efforts that our division has championed.”

Dr. Bryan Huang

Health Sciences Assistant Clinical Professor Bryan Huang, MD, will continue in his role as associate division chief.

Maynard will carry out his SHM duties largely from San Diego, with periodic visits to SHM headquarters in Philadelphia.

With a part-time appointment in Hospital Medicine, he will continue to be involved in the division’s clinical, teaching, and quality improvement activities.

He will also continue as chair of the UC San Diego Health System Patient Safety Committee.

Leading The Center in the Society of Hospital Medicine

The Society of Hospital Medicine (SHM) is the primary professional medical society for hospitalists. Its Center for Healthcare Improvement and Innovation, known as The Center, is a new division that gathers all quality improvement initiatives under Maynard’s direction.   |   Read the SHM press release >

Maynard has played influential roles in developing these initiatives. He has served as a leader in SHM collaboratives on venous thromboembolism (VTE) prevention, glycemic control, and transitions of care for older adults in the hospital.

A founder of the SHM’s Mentored Implementation Program, he has guided numerous hospital medicine programs through quality improvement processes that mirror what he and his colleagues have done at UC San Diego.

Now, as Senior Vice President of The Center, Maynard will oversee all QI initiatives and assist the SHM in designing its strategies for supporting and expanding its healthcare quality improvement efforts.

The Center provides a suite of QI tools and resources for hospitalists. Online collaboration programs offer expert guidance in VTE prevention, glycemic control, and transitions of care.

Through The Center, hospitalists can obtain mentored implementation programs, communicate with other QI program directors via a collaborative network, and access an online QI data repository.

The Agency for Healthcare Research and Quality recently recognized The Center as a Patient Safety Organization, which makes it possible for medical centers to submit protected health information to the SHM for analysis of patient safety events without violating HIPAA guidelines.

Leading the UC San Diego Center for Innovation and Improvement Science

UC San Diego Medical Center in Hillcrest The Center for Innovation and Improvement Science is a new entity that conducts quality improvement efforts in collaboration with UC San Diego Health System management, the Performance Improvement and Patient Safety Office, the Clinical and Translational Research Institute, and the Division of Biomedical Informatics.

As director of the CIIS, Maynard is leading UC San Diego’s efforts to address local and regional quality improvement goals:

  • Accelerating inpatient quality and safety initiatives and developing tools to assess their progress
  • Fostering QI skills in UC San Diego personnel and their collaborators and disseminating their successful QI tools through mentorship, consultation, and publication
  • Reviewing new technologies and fostering new research programs

One of the specific goals of the CIIS is to help other local and regional medical centers improve their quality of care, particularly in VTE prevention, glycemic control, anticoagulation management, and transitions of care.

Another goal is to disseminate UC San Diego’s findings and achievements, establishing UC San Diego more firmly as an innovative center and a leader in hospital quality and patient safety.

About Dr. Maynard

Dr. Greg MaynardGregory A. Maynard, MD, MSc, SFHM, Health Sciences Clinical Professor, has led the development of patient safety and hospital quality improvement protocols that have gone on to widespread implementation through the Society of Hospital Medicine, the Agency for Healthcare Research and Quality, the Institute for Healthcare Improvement, and the American Society of Health-System Pharmacists.

For their work in venous thromboembolism (VTE) prevention, Maynard and his colleagues received the SHM Team Approaches in Quality Improvement Award in 2008 and the Venous Disease Coalition’s Venous Research Award for Quality Improvement and Implementation of Best Practices in 2009.

Maynard received his MD degree at the University of Illinois and completed his residency and chief residency in Internal Medicine at Good Samaritan Regional Medical Center in Phoenix, Arizona.

Thereafter, he directed the Good Samaritan Hospital Medicine program and served as Senior Associate Director of the Internal Medicine Residency Program.

He earned his MSc in Clinical Research Design and Biostatistics from the University of Michigan in 1993.

Since Maynard came to UC San Diego in 2003, the Hospital Medicine program has expanded from 4 faculty members covering Thornton Hospital to 30 faculty hospitalists covering both Thornton Hospital and the UC San Diego Medical Center in Hillcrest.

Maynard has served as chair of the Inpatient Glycemic Control Committee, the Patient Discharge Process Improvement /Transitions of Care Committee, and the Patient Safety Committee. He has been leader of the VTE Management Task Force and co-leader of the Inpatient Osteoporosis Identification and Management Task Force.

The American College of Physicians named Maynard a Top Hospitalist in the United States in November 2008. This year, he received the UC San Diego School of Medicine’s Leadership and Innovation in Patient-Centered Systems Award.

About Dr. Seymann

Dr. Greg SeymannGregory B. Seymann, MD, SFHM, received his MD degree from UCLA in 1994 and completed his residency training in internal medicine at UC San Diego in 1997. Upon his graduation, he joined the UC San Diego Department of Medicine faculty as an assistant professor.

Seymann helped to found the original group of hospitalists at UC San Diego in 1998.

Seymann’s clinical and research interests are in community-acquired and healthcare-associated pneumonia, performance measurement for hospitals and physicians, systems-based quality improvement, and perioperative consult medicine.

In 2008, the San Diego County Medical Society and San Diego Magazine named Seymann to the “San Diego’s Top Doctors” list. In the same year, graduating housestaff honored him with their annual teaching award.

This year, he received the Medicine 401 Excellence in Teaching Award.

In the Society of Hospital Medicine, Seymann chairs the Academic Practice and Promotions Task Force and is a member of the Academic Hospitalist Committee, the Performance and Standards Committee, and the Ethics QI Research Subcommittee.

He is a member of the UC San Diego Patient Safety Committee. In the Department of Medicine, he is a member of the Committee on Advancement and Promotions, the Peer Review Committee, and the Executive Committee. He chairs the Division of Hospital Medicine Peer Review Committee.

Seymann is a member of the UC San Diego ORYX Core Measures Team for Community Acquired Pneumonia. ORYX is an initiative of the Joint Commission for Accreditation of Healthcare Organizations.

About Dr. Huang

Dr. Bryan HuangBryan Huang, MD, Health Sciences Assistant Clinical Professor, received his MD degree from UC San Francisco. He has been a member of the Hospital Medicine faculty since his graduation from internal medicine residency training at Stanford University in 2006.

Huang has special interest in the areas of prevention and management of delirium, prevention of falls, transitions of care, VTE prevention, and treatment of pneumonia.

He has completed additional training in quality improvement through the mini-advanced training program offered by Intermountain Healthcare in Salt Lake City, as well as the SHM Leadership Academy.

He served as the Thornton site director for the Core Clerkship in Internal Medicine in the School of Medicine until this June, and will continue to serve on the Medicine 401 course committee.

Huang served on the SHM Early Career Hospitalists committee from 2007 to 2010.

Together with Dr. Greg Seymann, he has served as associate division chief of Hospital Medicine for the past year. His responsibilities have included workflow redesign, scheduling, budgeting, recruitment, and working with the Internal Medicine Residency Program.

UC San Diego Health Sciences Receives Gift for Translational Research Building

$10 million from San Diego residents Steve and Lisa Altman will support the Clinical and Translational Research Institute

UC San Diego Health Sciences today announced that San Diego philanthropists and long-time residents Steve and Lisa Altman have pledged $10 million to the planned Clinical and Translational Research Institute (CTRI) building… Read the full story from the UCSD Newsroom

Dr. Gary Firestein, director of the Clinical and Translational Research Institute, is dean and associate vice chancellor of Translational Medicine for UC San Diego Health Sciences. He is Professor of Medicine in the Division of Rheumatology, Allergy and Immunology.

Schizophrenia Gene Mutation Found; Target for New Drugs

In a major advance for schizophrenia research, an international team of scientists, led by Jonathan Sebat, PhD, assistant professor of psychiatry and cellular and molecular medicine at the University of California, San Diego School of Medicine, has identified a gene mutation strongly linked to the brain disorder – and a signaling pathway that may be treatable with existing compounds. … Read the full story from the UCSD Newsroom

One of the co-authors of the study report is Marie Dell’Aquila, Ph.D., Clinical Professor of Medicine in the Division of Medical Genetics and Director of the Cytogenetics Laboratory for the UC San Diego Health System.