$5.6 Million Grant Renewal Expands Research in Kidney Failure

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDKD) – part of the National Institutes of Health – has renewed a grant shared by the University of California, San Diego and the University of Alabama at Birmingham Schools of Medicine. The five-year, $5.64 million renewal will extend and expand research into acute kidney failure, or acute kidney injury, which kills 70 to 80 percent of patients in intensive care units who develop the disease.Read the full story from the UCSD Newsroom


Dr. Ravindra MehtaRavindra L. Mehta, MD, FACP, UC San Diego professor of clinical medicine and vice chair for clinical research in the Department of Medicine, is associate director of the UC San Diego – University of Alabama at Birmingham O’Brien Center for Acute Kidney Injury Research.

He directs the O’Brien Center’s clinical studies core with co-director Daniel O’Connor, MD. O’Connor is professor of medicine and pharmacology and co-director, UCSD Center for Human Genetics and Genomics.

UC San Diego nephrology faculty members Roland Blantz, MD, and Volker Vallon, MD, are co-directors of the pre-clinical studies core of the O’Brien Center. Blantz is distinguished professor of medicine emeritus and former chief of the Division of Nephrology-Hypertension; Vallon is professor of medicine and pharmacology.

UC San Diego nephrologist Satish RamachandraRao, PhD, assistant professor of medicine, is a co-director of the Bioanalytical Resource Core.

Ravindra L. Mehta is Director of Dialysis Programs and Clinical Nephrology for UC San Diego Health System. In the UC San Diego School of Medicine, Mehta directs the Clinical Research Enhancement through Supplemental Training (CREST) and Master’s Degree in Clinical Research programs.

In 2011, Mehta received the International Society of Nephrology (ISN) Shire Bywaters Award for his lifetime achievements in acute kidney injury.

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$5.9 Million Grant to UC San Diego for Paradigm-Shifting Diabetes Research

Kumar Sharma, MD, FAHA, professor of medicine at the University of California, San Diego School of Medicine and director of the Center for Renal Translational Medicine, has received a $5.9 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health, to study kidney complications related to type 1 and type 2 diabetes…. Read the full story from the UCSD Newsroom


Kumar Sharma, MD, FAHADr. Sharma’s project, “Novel Paradigms in Diabetic Complications,” is a five-year Type 1 Diabetes Targeted Research Award.

Read the project abstract

Other Department of Medicine investigators in the project:

UCSD Nephrology Teaming with University of Alabama in O’Brien Center Grant

The Division of Nephrology in UC San Diego’s Department of Medicine has become part of a prestigious national kidney research network with the award of a five-year, $4.23 million O’Brien Research Center grant to the University of Alabama at Birmingham (UAB).

The project, which will bring about $400,000 annually to UCSD, will focus on finding new ways to prevent and to treat kidney failure.

Read the full story
from Health Sciences Communications

UCSD nephrologists, headed by Ravindra L. Mehta, M.D., F.A.C.P., will operate one of the core research efforts in the UAB/UCSD O’Brien Center.

Dr. Mehta, professor of clinical medicine in the Division of Nephrology, is Associate Chair for Clinical Affairs in the Department of Medicine.

Two other UCSD Nephrology researchers will contribute their research expertise in genetics and molecular markers of kidney injury:

The O’Brien Center funding comes from the National Institute of Diabetes and Digestive and Kidney Diseases. There are only eight O’Brien kidney research centers in the United States.

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