John Adamson Honored with American Society of Hematology Mentor Award for Basic Science

Dr.  John AdamsonThis week at its annual meeting in New Orleans, the American Society of Hematology (ASH) is presenting Dr. John W. Adamson with its 2013 Mentor Award for Basic Science.

John W. Adamson, MD, is clinical professor of medicine in the Division of Hematology-Oncology and associate director of the Hematology-Oncology Fellowship Training Program in the University of California, San Diego School of Medicine.

The ASH mentoring awards recognize hematologists who have had a significant, positive impact on their mentees’ careers and, through their mentees, have advanced research and patient care in the field of hematology.

The award cites Adamson for his passion for teaching the interrelationship between clinical medicine and biomedical science and the importance of granting early-career hematologists with protected time to develop their scientific skills.

Dr. Adamson has been particularly exceptional at forging bonds among early-career investigators with similar interests and has been an advocate for the advancement of women in hematology.

Several of his mentees have become leading experts in the field, and many have assumed leadership roles in the greater hematology research community.

Adamson is a past president of the American Society of Hematology and was editor of its official journal, Blood, from 1983 to 1987.

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Read the American Society of Hematology press release

Drug Targets Hard-to-Reach Leukemia Stem Cells Responsible for Relapses

Researchers at the University of California, San Diego School of Medicine have discovered that hard-to-reach, drug-resistant leukemia stem cells (LSCs) that overexpress multiple pro-survival protein forms are sensitive – and thus vulnerable – to a novel cancer stem cell-targeting drug currently under development. … Read the full story from the UCSD Newsroom

Catriona H. M. Jamieson, MD, PhDPrincipal investigator of the study is Catriona H. M. Jamieson, MD, PhD, associate professor of medicine in the Division of Hematology-Oncology and director of stem cell research at the UC San Diego Moores Cancer Center.

Dr. Jamieson is on the steering committee for the Moores Cancer Center’s My Answer to Cancer initiative for personalized cancer therapy. She is a member of the faculty in the UCSD Biomedical Sciences Graduate Program.

Citation for the report: Goff DJ, Recart AC, Sadarangani A, Chun H-J, Barrett CL, Krajewska M, Leu H, Low-Marchelli J, Ma W, Shih AY, Wei J, Zhai D, Geron I, Pu M, Bao L, Chuang R, Balaian L, Gotlib J, Minden M, Martinelli G, Rusert J, Dao K-H, Shazand K, Wentworth P, Smith KM, Jamieson CAM, Morris SR, Messer K, S.B. Goldstein LSB, Hudson TJ, Marra M, Frazer KA, Pellecchia M, Reed JC, and Jamieson CHM. (2013) A Pan-BCL2 Inhibitor Renders Bone-Marrow-Resident Human Leukemia Stem Cells Sensitive to Tyrosine Kinase Inhibition. Cell Stem Cell 10.1016/j.stem.2012.12.011, online January 17, 2013.

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DELPHI Project Foretells Future of Personalized Population Health

NSF awards $2 million over four years to UC San Diego computer scientists and physicians

Imagine a new type of healthcare app that does it all – it helps you understand your current health status, assists you in making changes in your life to improve your health, and takes into account the perspective of your entire life history, others in your age group–and perhaps even your neighborhood– who share similar characteristics.

That’s the vision put forward by a team of physicians and computer scientists at the University of California, San Diego who are collaborating on a new digital resource that would take advantage of advances in databases, cyberinfrastructure and machine learning to usher in a new era of health and health care…. Read the full story from the UCSD Newsroom

Dr. Lucila Ohno-MachadoLucila Ohno-Machado, MD, PhD, FACMI, is an investigator on the project, whose title is “Data E-platform Leveraged for Patient Empowerment and Population Health Improvement (DELPHI).”

Dr. Ohno-Machado is professor of medicine and founding chief of the Division of Biomedical Informatics. She directs, among other projects, another UCSD biomedical cyberinfrastructure, the Integrating Data for Analysis, Anonymizing and Sharing (iDASH) project. IDASH is a National Center for Biomedical Computing under the auspices of the NIH Roadmap for Bioinformatics and Computational Biology. Under AHRQ funding, she directs the related project Scalable National Network for Effectiveness Research (SCANNER).

Dr. Ohno-Machado’s research specialty is predictive modeling with an emphasis on calibration methods that combine phenotype and genotype/gene expression data for personalized medicine.

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UC San Diego Ranks 6th Among U.S. Universities for Research & Development Dollars

The University of California, San Diego again ranked 6th among top U.S. universities in total research and development expenditures for fiscal year 2010, with $580,279 million in federal R&D money and $943,219 million in total R&D expenditures. The numbers were announced by the National Science Foundation (NSF)…. Read the full story from the UCSD Newsroom

Researcher in laboratory at UC San Diego.
In fiscal year 2010-2011, the research funding in the Department of Medicine totaled $113.6 million from nearly 380 individual contracts and grants.

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2009 Funding Offered in New UCSD K12 Grant Program for Junior Faculty Investigators

Applications are now being accepted for a new, institutionally-funded grant program for junior faculty investigators at UCSD.

Offered through UCSD’s Clinical and Translational Research Institute (CTRI), the K12 grants are the institutional equivalent of a National Institutes of Health K23 or K08 mentored career development award.

Applications must be received January 9, 2009, for funding to begin July 1, 2009. All applicants will be notified by March 2, 2009.

Get application form and instructions

Eligible candidates include UCSD instructors or assistant professors in any academic series and fellows or postdocs who are completing their training. Applicants must secure their home departments’ approval before applying.

Each applicant and his/her home department must commit to the applicant’s 75% level of research effort through the project period.

In this first annual competition for the K12 funding, up to two investigators will receive support for up to 3 years from the Dean’s Office and from their home departments. The Dean’s Office and the home department each will grant $50,000 toward salary and benefits.

Funded investigators will be offered early didactic opportunities and in-depth formal and informal research mentoring through the UCSD CREST program.

UCSD’s CTRI K12 Program is directed by Joel E. Dimsdale, M.D., Distinguished Professor of Psychiatry. Dilip Jeste, M.D., Estelle and Edgar Levi Chair in Aging and Distinguished Professor of Psychiatry and Neurosciences, is Director of the CTRI Education and Community Alliances Division.

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