Cheap, green technique advances efforts toward malaria transmission vaccine in humans —
Researchers at University of California, San Diego School of Medicine used algae as a mini-factory to produce a malaria parasite protein. The algae-produced protein, paired with an immune-boosting cocktail suitable for use in humans, generated antibodies in mice that nearly eliminated mosquito infection by the malaria parasite. The method, published Feb. 17 by Infection and Immunity, is the newest attempt to develop a vaccine that prevents transmission of the malaria parasite from host to mosquito. … Read the full story from the UC San Diego Newsroom
Chronic gastrointestinal bleeding in a 50-year-old man from Ethiopia is the topic of a clinicopathological conference to be presented by Dr. Joseph M. Vinetz at Medicine Grand Rounds on November 12.
Joseph M. Vinetz, MD, is professor of medicine in the Division of Infectious Diseases, Department of Medicine at the UCSD School of Medicine. He is associate editor of the American Journal of Tropical Medicine and Hygiene and deputy editor of PLoS Neglected Tropical Diseases.
Infectious disease specialist Dr. Joseph Vinetz and colleagues have discovered a new species of bacteria that may be a major cause of a potentially fatal tropical disease.
The disease, leptospirosis, is transmitted from animals to humans. Severe forms of leptospirosis have high fatality rates.
Joseph Vinetz, M.D., is Professor of Medicine in the Division of Infectious Diseases. In the study, he collaborated with researchers at other North American centers and the Universidad Peruana Cayetano Heredia in Lima, Peru.
The study was published in the April 1 issue of Neglected Tropical Diseases:
Matthias MA, Ricaldi JN, Cespedes M, … and Vinetz, JM. Human Leptospirosis Caused by a New, Antigenically Unique Leptospira Associated with a Rattus Species Reservoir in the Peruvian Amazon. PLoS Negl Trop Dis. 2008 April; 2(4): e213. Published online 2008 April 2. doi: 10.1371/journal.pntd.0000213. Read the report