UC San Diego Endocrinologists Team with Pharmacists to Offer Diabetes “Tune Up” Clinic

Dr. Steven Edelman

Dr. Steven Edelman

Department of Medicine endocrinologists Steven V. Edelman, MD, (left) and Robert R. Henry, MD (below right), collaborate with Candis Morello, Pharm D, and students in the Skaggs School of Pharmacy and Pharmaceutical Sciences to offer a six-month Diabetes Intensive Medical Management (DIMM) “tune up” clinic for patients with complex cases of diabetes at the VA San Diego Healthcare System.

Dr. Robert Henry

Dr. Robert Henry

At each visit, a patient receives an hour of personalized attention to medication management, diet, exercise, controlling blood sugar levels and other necessities that may be involved in a complex case of diabetes.

The aim is to achieve glycemic control within the six-month period of the “tune up” clinic..

In a preliminary study, Drs. Morello, Evans, Henry and coworkers have assessed the outcomes of the clinic, and the findings indicate that this pharmacist-endocrinologist collaborative approach is effective.  |  Read the Study Abstract in the January 2016 issue of Annals of Pharmacotherapy  |  Read the full story from the UC San Diego Newsroom

Steven V. Edelman, MD, Clinical Professor in the Department of Medicine, directs the Diabetes Care Clinic at VA San Diego Healthcare System (VASDHS) and is an investigator in the VA Center for Metabolic Research. He is founder and director of Taking Control of Your Diabetes, a non-profit diabetes education organization. He conducts research focusing on developing and evaluating new treatments for type 1 and type 2 diabetes.

Robert R. Henry, MD, Professor in the Department of Medicine, is Chief of the VA Center for Metabolic Research and Chief of the Section of Endocrinology, Metabolism and Diabetes at VASDHS. In his research, he investigates the etiology, treatment, and prevention of obesity and type 2 diabetes.

Dr. Morello is Professor of Clinical Pharmacy and Associate Dean for Student Affairs at Skaggs School of Pharmacy and Pharmaceutical Sciences.

The study report was published online in November, 2015, and in print in January, 2016.

Clinical Trial To Test Safety of Stem Cell-Derived Therapy for Type 1 Diabetes

UC San Diego is initial site for first-in-human testing of implanted cell therapy

Researchers at the University of California, San Diego School of Medicine, in partnership with ViaCyte, Inc., a San Diego-based biotechnology firm specializing in regenerative medicine, have launched the first-ever human Phase I/II clinical trial of a stem cell-derived therapy for patients with Type 1 diabetes. … Read the full story from the UCSD Newsroom


Principal investigator in the study is Robert R. Henry, MD, professor of medicine in the Division of Endocrinology and Metabolism at UC San Diego and chief of the Section of Endocrinology, Metabolism & Diabetes at the Veterans Affairs San Diego Healthcare System.

New Division Chief and Vice Chief of Endocrinology and Metabolism

Announced July 28, 2014, by Wolfgang H. Dillmann, MD, Helen M. Ranney Distinguished Professor and Chair of the Department of Medicine

Dr. Nicholas Webster

Nicholas Webster, PhD

I am pleased to announce that an internal review committee has selected Dr. Nick Webster as the new chief of the Division of Endocrinology and Metabolism in the Department of Medicine. Dr. Nai-Wen Chi has been selected to serve as vice chief.

Wolfgang H. Dillmann, MD

Wolfgang H. Dillmann, MD

I would like to express my gratitude to Dr. Nick Webster, who accepted the role of interim division chief after I stepped down in 2010. In leading the Division of Endocrinology and Metabolism for the past four years, Dr. Webster has done an important service for the division and the department.

Nick Webster, PhD, professor of medicine, is Associate Director for Shared Resources at the Moores Cancer Center and holds a joint appointment as a Senior Research Career Scientist at the VA San Diego Healthcare System. He is a highly respected researcher and thought leader in the field of endocrinology and metabolism.

Dr. Webster earned his B.A. and M.A. from Cambridge University and his Ph.D. from Stanford University.  After a post-doctoral fellowship at the CNRS in Strasbourg, France, he joined the UCSD faculty in the Division of Endocrinology and Metabolism in 1989 and was promoted to Professor in 2006.

Dr. Webster has been very active in service to the University and the Veterans Affairs San Diego Healthcare System (VASDHS).  He has held a number of leadership positions at UCSD, including Associate Vice Chancellor for Research Facilities in the Office of Research Affairs, where his portfolio included oversight of the animal welfare program and university-wide shared resources.  Dr. Webster has served as chair of a number of university committees, including the Radiation Safety and Surveillance Committee, the Animal Program Oversight Committee, the Recruitment and Admission Committee for the Biomedical Sciences Graduate Program, the Shared Resources Oversight Committee, and the Research Space Committees at the VASDHS.

Over the past 25 years, Dr. Webster has maintained an active research program, which is broadly focused on the mechanisms of hormonal signal transduction and gene regulation in different developmental and disease contexts.  He actively participates in the Center for Reproductive Science and Medicine, the Diabetes Research Center, and the Center for Transdisciplinary Research in Energetics and Cancer.

Nai-Wen Chi, MD, PhD

Nai-Wen Chi, MD, PhD

The newly appointed vice chair of the Division of Endocrinology and Metabolism, Dr. Nai-Wen Chi, is a researcher and board-certified endocrinologist at the UCSD Medical Center and the VA. Dr. Chi earned his M.D. from National Taiwan University prior to receiving his Ph.D. from Harvard University, where he was mentored by Dr. Richard Kolodner in investigating the molecular machinery that maintains the yeast mitochondrial genome.  Dr. Chi then completed his medical residency and endocrine fellowship at the Massachusetts General Hospital.  During his postdoctoral fellowship at MIT, he was mentored by Dr. Harvey Lodish in identifying novel insulin-signaling molecules that regulate vesicular trafficking.

Dr. Chi joined the UCSD faculty in 2000 and has been the director of the Endocrine Fellowship since 2005.  His clinical interest focuses on dysnatremias while his research program takes biochemical and genetic approaches to investigate the pathophysiology of diabetes and obesity.

Please join me in giving your enthusiastic support to Drs. Nick Webster and Nai-Wen Chi in their new positions of leadership in the Department of Medicine.

UC San Diego Health System Retains #1 Ranking

US News & World Report Cites Region’s Only Academic Health System Among Nation’s Best 

UC San Diego Health System remains among the nation’s best, according to the U.S. News & World Report’s 2014-15 issue of “America’s Best Hospitals,” released this week. The magazine’s widely cited findings again placed UC San Diego Health System first in the San Diego metropolitan area and fifth in California, with national rankings in 11 specialties, up from 10 last year. This is comparable to the country’s most prestigious health care institutions.  Read the full story from the UCSD Newsroom


Sulpizio Cardiovascular CenterUC San Diego Health System is nationally ranked in eleven medical specialties, including seven in the Department of Medicine:  Cancer, Cardiology, Endocrinology & Diabetes, Gastroenterology, Geriatrics, Nephrology, Pulmonology and Rheumatology.

Four Common Antipsychotic Drugs Found to Lack Safety and Effectiveness in Older Adults

In older adults, antipsychotic drugs are commonly prescribed off-label for a number of disorders outside of their Food and Drug Administration (FDA)-approved indications – schizophrenia and bipolar disorder. The largest number of antipsychotic prescriptions in older adults is for behavioral disturbances associated with dementia, some of which carry FDA warnings on prescription information for these drugs.

In a new study – led by researchers at the University of California, San Diego School of Medicine, Stanford University and the University of Iowa, and funded by the National Institute of Mental Health – four of the antipsychotics most commonly prescribed off label for use in patients over 40 were found to lack both safety and effectiveness. … Read the full story from the UCSD Newsroom


Department of Medicine endocrinology and metabolism researchers Robert R. Henry, MD, and Sunder Mudaliar, MD, are coinvestigators in the study of the antipsychotic drugs.Dr. Robert R. Henry

Robert R. Henry, MD, is professor of medicine in the Division of Endocrinology & Metabolism at UC San Diego. At the Veterans Affairs San Diego Healthcare System (VASDHS), he is Chief of the Section of Endocrinology, Metabolism & Diabetes and Director of the Center for Metabolic Research.

Sunder Mudaliar, MD, is health sciences clinical professor in the Division of Endocrinology & Metabolism at UCSD. He is extensively involved in medical teaching and clinical care at the VASDHS. As an investigator in the Center for Metabolic Research, he performs clinical research focused on the prevention and treatment of diabetes.

More information:

Citation for the study report: Jin H, Shih PB,Golshan S, Mudaliar S, Henry R, Glorioso DK, Arndt S, Kraemer HC, Jeste DV. Comparison of Longer-Term Safety and Effectiveness of 4 Atypical Antipsychotics in Patients Over Age 40: A Trial Using Equipoise-Stratified Randomization. E-pub ahead of print, November 27, 2012, The Journal of Clinical Psychiatry.

New Way of Fighting High Cholesterol Upends Assumptions

Atherosclerosis – the hardening of arteries that is a primary cause of cardiovascular disease and death – has long been presumed to be the fateful consequence of complicated interactions between overabundant cholesterol and resulting inflammation in the heart and blood vessels. … Read the full story from the UCSD Newsroom


Christopher K. GlassSenior author of the study report is Christopher K. Glass, MD, PhD, pictured at left, professor in the Departments of Medicine and Cellular and Molecular Medicine.

The other Department of Medicine coauthors on the study report are Andrew C. Li, MD, PhD, assistant professor of medicine in the Division of Endocrinology and Metabolism; Sotirios Tsimikas, MD, FACC, professor of clinical medicine in the Division of Cardiovascular Medicine; and Oswald Quehenberger, PhD, professor of medicine in the Division of Endocrinology and Metabolism.

Read the report of the study in Cell (full text UCSD only)

Citation of study report: Spann NJ, Garmire LX, McDonald JG, Myers DS, Milne SB, Shibata N, Reichart D, Fox JN, Shaked I, Heudobler D, Raetz CRH, Wang EW, Kelly SL, Sullards MC, Murphy RC, Merrill AH Jr, Brown HA, Dennis EA, Li AC, Ley K, Tsimikas S, Fahy E, Subramaniam S, Quehenberger O, Russell DW, Glass CK. Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses. Cell 151(1):138-152, 2012. http://dx.doi.org/10.1016/j.cell.2012.06.054

“Taking Control of Your Diabetes” Wins an Aurora Award for UCSD-TV

Dr. Steven Edelman“Taking Control of Your Diabetes,” a UCSD-TV series hosted by Dr. Steven Edelman, is one of two UCSD-TV programs to win an Aurora Award for outstanding quality this year. The weight management episode of the series won a Gold Award in the Fitness/Health category.

Steven V. Edelman, MD, pictured at left, is Professor of Medicine in the Division of Endocrinology and Metabolism.

Read the full story from UCSD-TV

Ranked #1: UC San Diego Health System Ranks First in U.S. News & World Report’s Best Hospitals for Metro Areas

UC San Diego Health System has been ranked first in San Diego in U.S. News & World Report’s first-ever Best Hospitals metro area rankings, available online at www.usnews.com/hospitals. This prestigious ranking recognizes UC San Diego Health System as a leader in delivering groundbreaking health care to southern California…. Read the full story from the UCSD Newsroom

UCSD SignUC San Diego Health System is nationally ranked in five medical specialties, including three in the Department of Medicine: Pulmonology, Diabetes and Endocrinology and Geriatrics.

To Prevent Heart Disease, Treat High Cholesterol Early in life, Dr. Daniel Steinberg and colleagues say

Early childhood is the time to start lowering cholesterol to prevent heart disease, according to Dr. Daniel Steinberg and colleagues at UCSD.

Daniel Steinberg, M.D., Ph.D., is Emeritus Professor of Medicine in the Division of Endocrinology & Metabolism. He is renowned for his groundbreaking research in cholesterol and atherosclerosis.

Read the full story from UC San Diego
Health Sciences Communications

His colleagues and co-authors, Christopher K. Glass, M.D., Ph.D., and Joseph Witztum, M.D., are both professors of medicine. All three researchers are members of the Division of Endocrinology & Metabolism.

Their analysis and recommendations are published in the August 5 issue of the journal Circulation.

Citation for the article:  Steinberg, Daniel MD, PhD; Glass, Christopher K. MD, PhD; Witztum, Joseph L. MD. Evidence Mandating Earlier and More Aggressive Treatment of Hypercholesterolemia. Circulation 2008 August 5;118(6):172-177. – |  Read the article (PDF)

More Information: