HIV Infection Prematurely Ages People by an Average of Five Years

Epigenetic changes also associated with 19 percent increased risk of mortality —

Thanks to combination antiretroviral therapies, many people with HIV can expect to live decades after being infected. Yet doctors have observed these patients often show signs of premature aging. Researchers at University of California San Diego School of Medicine and the University of Nebraska Medical Center have applied a highly accurate biomarker to measure just how much HIV infection ages people at the cellular level — an average of almost five years.

The study is published April 21 in Molecular Cell. … Read the Full Story from the UC San Diego Newsroom


Trey Ideker, PhD

Trey Ideker, PhD

Trey Ideker, PhD, Professor of Medicine and Professor of Bioengineering, is co-corresponding author of the study report in Molecular Cell (article access for UC San Diego only).

Other Department of Medicine authors include Andrew M. Gross, Philipp A. Jaeger, Jason F. Kreisberg and Katherine Licon.

New Video Series Chronicles AIDS Epidemic in Tijuana

“HIV/SIDA: The Epidemic in Tijuana” focuses on UC San Diego researchers’ efforts to track and prevent the spread of HIV among the city’s most at-risk populations —

The new documentary “HIV/SIDA: The Epidemic in Tijuana” offers an unflinching look at the challenges facing researchers from the University of California, San Diego as they attempt to identify and treat people who inject drugs, sex workers, transgender women and others who are at high risk for HIV infection in Tijuana. The program, which was shot over two years, premieres Oct. 5 at 8 p.m. on UCSD-TV and can be viewed at www.uctv.tv/hiv-sida. … Read the full story from the UC San Diego Newsroom


The film features the efforts of Dr. Steffanie Strathdee, her Division of Global Public Health colleagues and a multidisciplinary, multinational team of medical professionals to trace and arrest the spread of AIDS in Tijuana.

Dr. Strathdee is Associate Dean of Global Health Sciences, Harold Simon Professor and Chief of the Division of Global Public Health at UC San Diego.

The four-part documentary, based on the book Tomorrow Is a Long Time by Malcolm Linton and Jon Cohen, premiered on UCSD-TV on October 5. It was supported by funding from the Ford Foundation.

Find more about the documentary here: HIV/SIDA: The Epidemic in Tijuana – UCSD-TV – University of California Television.