Herpes Infected Humans Before They Were Human

The virus originated in chimpanzees, jumping into humans 1.6 million years ago

Researchers at the University of California, San Diego School of Medicine have identified the evolutionary origins of human herpes simplex virus (HSV) -1 and -2, reporting that the former infected hominids before their evolutionary split from chimpanzees 6 million years ago while the latter jumped from ancient chimpanzees to ancestors of modern humans – Homo erectus – approximately 1.6 million years ago. … Read the full story from the UC San Diego News Center

Herpes Virus Exploits Immune Response to Bolster Infection

Researchers at the University of California, San Diego School of Medicine and colleagues report that the herpes simplex virus type-1 (HSV-1), which affects an estimated 50 to 80 percent of all American adults, exploits an immune system receptor to boost its infectivity and ability to cause disease. … Read the full story from the UCSD Newsroom


Dr. Richard Gallo

Dr. Richard Gallo

Richard L. Gallo, MD, PhD, left, is principal investigator of the study, which is reported in the online-only journal Nature Communications.

Gallo is professor of medicine and chief of the Division of Dermatology.

Citation for the study report:  Daniel T. MacLeod, Teruaki Nakatsuji, Kenshi Yamasaki, Lester Kobzik & Richard L. Gallo. HSV-1 exploits the innate immune scavenger receptor MARCO to enhance epithelial adsorption and infection. Nature Communications 4, Article number: 1963. doi:10.1038/ncomms2963. Published 06 June 2013.  |  Abstract

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