E-Cigarette Vapor Boosts Superbugs and Dampens Immune System

In lab and mouse experiments, exposure promotes bacterial virulence and inflammation, while blocking the body’s ability to fight infection —

Researchers at the University of California, San Diego School of Medicine and Veterans Affairs San Diego Healthcare System report data suggesting that e-cigarettes are toxic to human airway cells, suppress immune defenses and alter inflammation, while at the same time boosting bacterial virulence. The mouse study is published January 25 by the Journal of Molecular Medicine.

“This study shows that e-cigarette vapor is not benign — at high doses it can directly kill lung cells, which is frightening,” said senior author Laura E. Crotty Alexander, MD, … Read the full story from the UC San Diego Newsroom

Laura E. Crotty Alexander, MD

Laura E. Crotty Alexander, MD

Senior author Laura E. Crotty Alexander, MD, is Assistant Professor of Medicine in the Division of Pulmonary, Critical Care & Sleep Medicine in the Department of Medicine and staff physician at the Veterans Affairs San Diego Healthcare System.

The article reporting the findings was published first online on January 25, 2016.  Article abstract  |  Full text of article (UC San Diego Only)

In the Media: Dr. Richard Clark

Dr. Richard Clark is one of the three experts interviewed in the KPBS These Days segment, “The Science of Substance Abuse.”

Richard F. Clark, M.D., Professor of Clinical Medicine, directs the Division of Medical Toxicology in Emergency Medicine. He is medical director of the San Diego Division of the California Poison Control System at UCSD Medical Center.