This year’s San Diego Magazine/San Diego County Medical Society Top Doctors list includes 41 Department of Medicine faculty clinicians. View photo gallery
Announcement for UC Investigators
Gary S. Firestein, MD
Chair, University of California Biomedical Research
Acceleration, Integration and Development (UCBRAID)
Professor of Medicine
Dean and Associate Vice Chancellor, Translational Medicine
Director, Clinical and Translational Research Institute
UC San Diego
The University of California Biomedical Research Acceleration, Integration and Development (UC BRAID; ucbraid.org) is pleased to announce the launch of the UC Research eXchange (UC ReX) and the UC ReX Data Explorer tool. This system enables exploration of a combined population of over 12 million patients from medical center databases at UC Los Angeles, UC Irvine, UC Davis, UC San Diego, and UC San Francisco.
UC ReX Data Explorer gives researchers and quality specialists access to cohort counts derived from de-identified clinical data collected at the point of care to improve medical care and advance research.
UC ReX was initiated by UC BRAID in 2011 with a 5-year grant of $5 million from the UC Office of the President (UCOP) and developed through a collaboration of the medical campuses and their Chief Information Officers and CTSAs.
An important part of UC BRAID’s mission is to improve UC collaborative research opportunities. UC ReX is a great example of how UC BRAID facilitates integration of research programs, clinical informatics, technology, and resources across University of California campuses.
In the years since the best-selling book “The Immortal Life of Henrietta Lacks” made the issue of informed consent and patient privacy a national topic of conversation, scientists and clinicians have continued to struggle to develop a comprehensive methodology for collecting and sharing data from patients and research subjects without jeopardizing their rights.
The University of California, San Diego’s iDASH project aims to address some of these fundamental challenges to research progress with its most recent series of “Driving Biological Projects” (DBPs) … Read the full story from the UCSD Newsroom
Lead investigator in the iDASH project is Lucila Ohno-Machado, MD, MBA, PhD, professor of medicine, founding chief of the Division of Biomedical Informatics and associate dean for informatics and technology at UC San Diego.
Among other research and education projects directed by Dr. Ohno-Machado are the Biomedical Research Informatics for Global Health training program and the biomedical informatics component of the UC San Diego – Universidade Eduardo Mondlane Medical Education Partnership Initiative. | See all DBMI research projects
Dr. Ohno-Machado joined the UC San Diego faculty from Harvard Medical School in 2009. She was elected to the American Society for Clinical Investigation in 2010.
- Dr. Ohno-Machado’s academic profile
- UC San Diego Receives Two Major Biomedical Informatics Grants – UC San Diego press release.
- Introductory webinars for the three iDASH 2013-2015 Driving Biological Projects:
- Partnership for Epidemiological Research in Hispanic/Latinos: Research Literacy to Consent to Bio-behavioral Longitudinal Research (recording) – Sheila Castañeda and Greg Talavera, San Diego State University, August 22, 2013
- Privacy Preserving Analytics for Kawasaki Disease in African-Americans (recording) – Jane Burns and Jihoon Kim, UC San Diego, August 6, 2013
- Informed Consent for Biospecimen Collection and Data Sharing among Low-income, Uninsured and Underinsured Women: Is it a Matter of Trust? (recording) – Elena Martinez, Moores Cancer Center, and Ian Komenaka, Maricopa Medical Center, August 2, 2013
- Biomedical Research Informatics for Global Health Training (BRIGHT) Program – press release
- UC San Diego – Universidade Eduardo Mondlane Medical Education Partnership Initiative (MEPI)
On March 19, the National Comprehensive Cancer Network® (NCCN®) announced the election of University of California, San Diego Moores Cancer Center as the first and only San Diego-based NCCN Member Institution dedicated to improving the quality, effectiveness, and efficiency of care provided to patients with cancer. … Read the full story from the UCSD Newsroom
In “The Fat You Can’t See,” Loomba describes the rising incidence of fatty liver disease and points to society’s general increase in dietary sugar intake as a major cause. He emphasizes the importance of identifying individuals who are at highest risk for developing the disease and he predicts there will be a dramatic increase in our understanding of the disease in the next five years.
Rohit Loomba, MD, MHSc, is assistant professor of clinical medicine in the Division of Gastroenterology. He also holds an appointment in the Division of Epidemiology in the Department of Family and Preventive Medicine.
Loomba conducts his clinical practice in UC San Diego Health System’s liver disease clinics. In his research laboratory, he conducts a variety of studies of nonalcoholic fatty liver disease (NAFLD), including a number of clinical trials.
With a four-year mentored patient-oriented research career development grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Loomba is investigating the genetic epidemiology of NAFLD in a twin-pair study. In that work, his mentors are UCSD researchers Daniel T. O’Connor, MD, professor of medicine and pharmacology; Elizabeth Barrett-Connor, MD, distinguished professor and chief of the Division of Epidemiology in the Department of Family and Preventive Medicine; and David Brenner, MD, Vice Chancellor for Health Sciences and Dean of the School of Medicine.
Loomba serves as the UCSD site principal investigator for the Nonalcoholic Steatohepatitis Clinical Research Network (NASH-CRN) studies in adult patients with NAFLD. NASH-CRN, an NIDDK-sponsored research consortium funded via a UO1 research program-cooperative agreement mechanism, aims to improve understanding of the natural history, pathophysiology and management of NAFLD.
In addition, he is the founding director and principal investigator of the San Diego Integrated NAFLD Research Consortium (SINC), which includes four centers: UCSD, Kaiser Permanente Health System, Sharp Health System, and Balboa Naval Medical Center. SINC is a collaborative network that allows community-based patients to participate in NAFLD studies conducted at UCSD.
Loomba has established a major NAFLD research program at UCSD with recently published investigator-initiated treatment studies in NASH (Le et al., Hepatology September 2012) and several in progress.
In various NAFLD translational research studies currently ongoing at UCSD, Loomba collaborates with Drs. Jerrold Olefsky, David Brenner, Claude Sirlin, Bernd Schnabl, Lars Eckmann, Edward Dennis, Ariel Feldstein and Ekihiro Seki.
He also directs the UCSD fellowship training program in liver epidemiology and patient-oriented outcomes research.
Verizon Foundation to provide grant and in-kind technology solutions to scale up novel approach to monitoring adherence to TB treatment
As part of an innovative philanthropic health care program targeting reduction of health care disparities in diverse communities around the United States, the Verizon Foundation has provided the University of California, San Diego School of Medicine with a $300,000 grant, as well as important in-kind health information technology solutions.
The support from Verizon will allow researchers from the University to more quickly scale-up a mobile phone-based solution that they developed to overcome the high cost and other barriers to monitoring tuberculosis patients throughout their treatment…. Read the full story from the UCSD Newsroom
Leading the program is Richard Garfein, PhD, MPH, left, professor of medicine in the Division of Global Public Health. Dr. Garfein, an infectious disease epidemiologist, joined the UC San Diego faculty from the Centers for Disease Control and Prevention in 2005.
He is conducting the project in collaboration with the California Institute for Telecommunications and Information Technology (Calit2).
At right, Dr. Garfein’s daughter demonstrates a smartphone video app that makes it possible for a distant clinician to confirm that a patient has taken a dose of tuberculosis medication.
The approach is called “video directly observed therapy” (VDOT). Dr. Garfein and collaborators have demonstrated the feasibility, acceptability and potential efficacy of VDOT in an NIH-funded pilot study in San Diego and Tijuana. Their mHealth Summit Meeting abstract for the project is published in the Journal of Mobile Technology in Medicine.
In the next six months, with the Verizon Foundation’s assistance, they will expand the VDOT smartphone app for broader use.
“This is a new and exciting direction and a new funding source for UCSD,” said Steffanie Strathdee, PhD, Associate Dean of Global Health Sciences and Harold Simon Professor and Chief of the UC San Diego Division of Global Public Health.
She directs the UC San Diego Global Health Initiative and is founding co-director of the UC Global Health Institute’s Center for Migration and Health.
- Details of the project
- mHealth Summit Meeting abstract in the Journal of Mobile Technology in Medicine
- Other news stories about Dr. Garfein’s work:
- Adding Nucleic Acid Testing to HIV Screening May Help Identify More People with HIV – June 15, 2010
- Burden of HIV/TB Infections Increasingly Falling on Hispanic Community – February 10, 2010
- Tijuana Injection Drug Users on Collision Course for HIV and TB – April 15, 2009
- New UCSD Cross-Border Program Aims to Assess and Treat Tuberculosis in Tijuana – September 28, 2006
UC San Diego Medical Center, located in Hillcrest, has been named one of the nation’s 100 Top Hospitals® by Thomson Reuters. Ranked among the country’s major teaching hospitals, the Medical Center was also one of twelve hospitals to receive the Everest Award. This award honors hospitals that have achieved both the highest current performance and the fastest long-term improvement over a five-year period in Reuter’s national benchmarking study…. Read the full story from the UCSD Newsroom
On December 12, 2011, UC San Diego Health System was bestowed Magnet® status by the American Nurses Credentialing Center (ANCC). The Magnet Recognition Program® recognizes health care organizations for quality patient care, nursing excellence and innovations in nursing practice. UC San Diego Health System is one of 25 health systems in California to achieve this prestigious recognition…. Read the full story from the UCSD Newsroom
Magnet® and Magnet Recognition Program® are registered trademarks of the American Nurses Credentialing Center. All rights reserved.
Lifesaving cardiac treatment time exceeds national guidelines
Over the last year, UC San Diego Health System managed to significantly decrease average door-to-balloon time, beating national guidelines by over a third, and improving care of patients with the most severe type of heart attack, known as STEMI (ST-segment-elevation myocardial infarction)… Read the full story from the UCSD Newsroom >>
Ehtisham “Shami” Mahmud, MD, FACC, pictured above left, chairs UC San Diego Health System’s Door-to-Balloon Time Committee. Dr. Mahmud is Chief of Clinical Cardiovascular Medicine, Co-Director of the Sulpizio Cardiovascular Center, and Professor of Medicine.
UC San Diego Sulpizio Cardiovascular Center (SCVC) will officially open its doors to the public on Monday, August 8 after the California Department of Public Health (CDPH) certified the SCVC for patient care. The region’s first cardiovascular center is now accessible to the tens of thousands of Californians who are at risk for or suffer from heart disease and stroke. … Read the full story from the UCSD Newsroom