Injectable Gel Could Repair Tissue Damaged by Heart Attack

University of California, San Diego researchers have developed a new injectable hydrogel that could be an effective and safe treatment for tissue damage caused by heart attacks. The study by Karen Christman and colleagues appears in the Feb. 21 issue of the Journal of the American College of Cardiology … Read the full story from the UCSD Newsroom

The UCSD research team includes Dr. Anthony DeMaria. Anthony N. DeMaria, MD, founding director of the Sulpizio Cardiovascular Center, holds the Judith and Jack White Chair in Cardiology.  |  Read the research report

UC San Diego Health System Now Offers Latest Catheter Ablation Therapy Using Heat Energy for Patients with Abnormal Heart Rhythms

FDA-approved non-surgical technology alters heart tissue that triggers atrial fibrillation

UC San Diego Sulpizio Cardiovascular Center is now offering patients with atrial fibrillation the breakthrough benefits of heat energy, or radio frequency waves, to irreversibly alter heart tissue that triggers an abnormal heart rhythm or arrhythmia. The THERMOCOOL® SF Catheter is an FDA-approved outpatient procedure for an early-stage form of the condition called paroxysmal atrial fibrillation, when recurring symptoms are unresponsive to medicine. … Read the full story from the UC San Diego Health System Newsroom

Dr. Gregory Feld, who directs the Cardiac Electrophysiology Program at the UC San Diego Sulpizio Cardiovascular Center, describes the new treatment in the news release excerpted above.

Gregory Feld, MD, is professor of medicine in clinical cardiovascular medicine. In 2011, he was named to both the national “Top Doctors” list from U.S.News & World Report and the “San Diego’s Top Doctors” list from the San Diego County Medical Society and San Diego Magazine.

New Study Upends Thinking About How Liver Disease Develops

In the latest of a series of related papers, researchers at the University of California, San Diego School of Medicine, with colleagues in Austria and elsewhere, present a new and more definitive explanation of how fibrotic cells form, multiply and eventually destroy the human liver, resulting in cirrhosis… Read the full story from the UCSD Newsroom

Pictured above is David Brenner, MD, Vice Chancellor for Health Sciences and dean of the UC San Diego School of Medicine, who is senior author of the research report.  First author of the study is Dr. Christoph H. Österreicher of the Biomedical Genomics (BIOGEM) Microarray Facility in the UCSD Department of Medicine, the Laboratory of Gene Regulation and Signal Transduction in the UCSD Department of Pharmacology, and the Medical University of Vienna. Other Department of Medicine coauthors are Drs. Melitta Penz-Österreicher (Medical University of Vienna), Roman Šášik, and BIOGEM director Dr. Gary Hardiman.

Read the report in the Proceedings of the National Academy of Sciences.

Researchers Create Atlas of Transcription Factor Combinations

Trey Ideker, Ph.D., Associate Professor of Medicine and Bioengineering and Chief of the Division of Medical Genetics, is principal investigator of the project described in the UCSD Newsroom story, “Researchers Create Atlas of Transcription Factor Combinations.”  |  Read the story

A Boon for Hepatitis C Research: Dr. Martina Buck Develops First Tissue Culture Model

Dr. Martina Buck, faculty researcher in the Division of Gastroenterology, has developed the first tissue culture system for the Hepatitis C virus. The system offers a model in which investigators can more easily test potential treatments for Hepatitis C.

Her report of the system is published in PLoS ONE.

Martina Buck, Ph.D., is Assistant Professor of Medicine in the Division of Gastroenterology and a researcher in the Tumor Growth, Invasion and Metastasis Program at the Moores UCSD Cancer Center.

Read the full story from
UC San Diego Health Sciences Communications

Citation for the report: Buck M (2008) Direct Infection and Replication of Naturally Occurring Hepatitis C Virus Genotypes 1, 2, 3 and 4 in Normal Human Hepatocyte Cultures. PLoS ONE 3(7): e2660. doi:10.1371/journal.pone.0002660  |  Read the report (free full text)

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