Researchers Boost Body’s Inflammation-Reduction Mechanism to Combat Obesity-Fueled Disease

Researchers at University of California, San Diego School of Medicine and University College Dublin (UCD) have found that augmenting a naturally occurring molecule in the body can help protect against obesity-related diseases by reducing inflammation in the fat tissues. The study, published June 4 in the journal Cell Metabolism, focused on liver and kidney diseases, but the researchers believe it could lead to a new therapeutic approach for a variety of obesity-fueled conditions.

“This is a new way of reducing inflammation and protecting organs, using a compound that’s already produced by the body,” said co-senior author Kumar Sharma, MD, a professor of medicine and director of the Center for Renal Translational Medicine at UC San Diego School of Medicine. “Essentially, we’re boosting the body’s natural response for reducing inflammation and showing the benefit in obesity-driven diseases.” … Read the full story from the UC San Diego Newsroom

Live Long and Measure: Quest to Create Real-World Tricorder

XPRIZE teams will test Star Trek-inspired medical devices at UC San Diego —

Seeking to boldly go where medical science has not gone before, the Clinical and Translational Research Institute (CTRI) at the University of California, San Diego has been named the official testing site for the $10 million Qualcomm Tricorder XPRIZE, a global competition sponsored by the Qualcomm Foundation to develop a consumer-friendly, mobile device capable of diagnosing and interpreting 15 physiological conditions and capturing vital health metrics.

The XPRIZE competition is inspired by the tricorder medical device that debuted in the original 1966 Star Trek TV show and was frequently featured in subsequent series and movies. …Read the full story from the UC San Diego Newsroom


Dr. Gary FiresteinGary S. Firestein, MD, is director of the CTRI and dean and associate vice chancellor of translational medicine at UC San Diego.

He is professor of medicine in the Division of Rheumatology, Allergy and Immunology and served as division chief from 1998 until he stepped down in 2010 to focus on his growing responsibilities as dean of translational medicine and director of the CTRI for UC San Diego Health Sciences.