Study Shows Certain Gastrointestinal Tumors Associated with Higher Mortality

Researchers at University of California, San Diego School of Medicine have determined that certain gastrointestinal stromal tumors (GISTs) are more deadly than previously reported in medical literature. Findings are published online in the Journal of Gastrointestinal Surgery. … Read the Full Story from the UC San Diego Newsroom


Paul Fanta, MD, MS

Paul Fanta, MD, MS

Paul T. Fanta, MD, Health Sciences Associate Clinical Professor of Medicine in the Division of Hematology-Oncology, is a study coauthor.

UC San Diego, UC San Francisco Launch New Cancer Cell Mapping Initiative

Researchers from the University of California, San Diego School of Medicine and University of California, San Francisco, with support from a diverse team of collaborators, have launched an ambitious new project – dubbed the Cancer Cell Map Initiative or CCMI – to determine how all of the components of a cancer cell interact.

“We’re going to draw the complete wiring diagram of a cancer cell,” said Nevan Krogan, PhD, director of the UC San Francisco division of QB3, a life science research institute and accelerator, an investigator at Gladstone Institutes and co-director of CCMI with Trey Ideker, PhD, chief of medical genetics in the UC San Diego Department of Medicine and founder of the UC San Diego Center for Computational Biology & Bioinformatics. … Read the full story from the UC San Diego Newsroom

 


Trey Ideker, PhD

Trey Ideker, PhD

Trey Ideker, PhD, is professor of bioengineering and professor of medicine in the Division of Medical Genetics. He was recently named a fellow of the American Association for the Advancement of Science (AAAS).

Dr. Ideker’s Laboratory Website

Anti-Leukemia Drug May Also Work Against Ovarian Cancer

An antibody therapy already in clinical trials to treat chronic lymphocytic leukemia (CLL) may also prove effective against ovarian cancer – and likely other cancers as well, report researchers at the University of California, San Diego School of Medicine in a study published in the Nov. 17 online early edition of the Proceedings of the National Academy of Sciences (PNAS).

The findings extend the anti-cancer potential of an experimental monoclonal antibody called cirmtuzumab, developed at UC San Diego Moores Cancer Center by Thomas Kipps, MD, PhD, and colleagues. Cirmtuzumab is currently in a first-in-human phase 1 clinical trial to assess its safety and efficacy in treating CLL. … Read the full story from the UC San Diego Newsroom


Dr. Thomas Kipps

Dr. Thomas Kipps

Thomas Kipps, MD, PhD, Evelyn and Edwin Tasch Chair in Cancer Research, is professor of medicine in the Division of Hematology-Oncology and deputy director of research at the UC San Diego Moores Cancer Center.

Dr. Kipps directs the multi-institutional, National Institutes of Health (NIH)-sponsored CLL Research Consortium (CRC) and UC San Diego Blood Cancer Research Fund.

Richard D. Kolodner Elected to Institute of Medicine

University of California, San Diego School of Medicine researchers Joseph G. Gleeson, MD, Howard Hughes Medical Institute investigator and professor of neurosciences and pediatrics, and Richard D. Kolodner, PhD, professor of medicine and Ludwig Cancer Research scientist, have been named new members of the Institute of Medicine (IOM), considered among the highest honors in the fields of health and medicine. … Read the full story from the UC San Diego News Center


Dr. Richard KolodnerGeneticist and biochemist Richard D. Kolodner, PhD, is a distinguished professor in the departments of medicine (Division of Hematology-Oncology) and cellular and molecular medicine at UC San Diego.

Kolodner co-leads the Laboratory of Cancer Genetics in the San Diego branch of the Ludwig Institute for Cancer Research, which is located at UC San Diego.

At the UC San Diego Moores Cancer Center, he co-leads the Cancer Genomes and Networks research program with Trey Ideker, PhD, and is a member of the faculty of the Cancer Therapeutics Training (CT2) Program.

He is also a member of the Institute for Genomic Medicine and the Biomedical Sciences graduate program.

Kolodner was elected to the National Academy of Sciences in 2000 and the American Academy of Arts and Sciences in 2008. His election to the Institute of Medicine brings to 10 the number of Department of Medicine faculty members who are members of the institute.

See other UC San Diego news stories about Dr. Kolodner and his work.

Dr. Webster Cavenee Named a Fellow of the American Association for Cancer Research Academy

Dr. Webster Cavenee Webster K. Cavenee, PhD, distinguished professor of medicine and director of the UC San Diego branch of the Ludwig Institute for Cancer Research, is one of five UCSD cancer researchers who have been named inaugural fellows of the American Association for Cancer Research Academy.

Election to the Academy recognizes researchers who have made exceptional contributions to cancer and/or cancer-related biomedical science. It is the highest honor given by the AACR.

Dr. Cavenee and the other honorees will be inducted into the Academy on April 5, the eve of the AACR Annual Meeting 2013 in Washington, DC.

More Information:

Gorder Walk Raises Funds for Melanoma Research at UC San Diego Moores Cancer Center Sept. 24

Event emphasizes early detection with the “ABCDE’s” of melanoma

The University of California, San Diego will host the 18th annual Bruce Gorder 5K Walk for Melanoma Sept. 24 on the university campus. The event brings the community together to raise funds for melanoma research at the UC San Diego Moores Cancer Center, as well as build awareness for prevention and early detection of the disease. … Read the full story from the UCSD Newsroom


The Gorder Walk raises private funds to support the melanoma research of Dr. Greg Daniels and colleagues. Gregory A. Daniels, MD, PhD, is Health Sciences Associate Clinical Professor in the Division of Hematology-Oncology and director of the Melanoma Unit at UC San Diego Moores Cancer Center.

Thomas Kipps Receives ACGT Investigator Award

Grant will help fund further testing of gene therapy treatment for leukemia patients

Citing his on-going development of an immune-mediated gene therapy for intractable B cell leukemia, the Alliance for Cancer Gene Therapy (ACGT) has awarded Thomas J. Kipps, MD, PhD, professor of medicine in the University of California, San Diego School of Medicine and deputy director of research operations at the UC San Diego Moores Cancer Center, its 2010 Investigator Award in Clinical Translation of Cell and Gene Therapy…. Read the full story from the UCSD Newsroom

Thomas J. Kipps, MD, PhD, is Professor of Medicine in the Division of Hematology-Oncology and deputy director of the UC San Diego Moores Cancer Center. He holds the Evelyn and Edwin Tasch Chair in Cancer Research. Read more about his research.

A Cancer Marker and Treatment in One?

UC San Diego Researchers Find Promise in Non-Human Sialic Acid Antibodies

Researchers at the University of California, San Diego School of Medicine say antibodies to a non-human sugar molecule commonly found in people may be useful as a future biomarker for predicting cancer risk, for diagnosing cancer cases early and, in sufficient concentration, used as a treatment for suppressing tumor growth…. Read the full story from the UCSD Newsroom

Dr. Richard Schwab and Dr. Ajit Varki (pictured above left), led the study, which was a multicenter collaboration that included the departments of Medicine and of Cellular and Molecular Medicine, Moores Cancer Center, and the Glycobiology Research and Training Center at UC San Diego.

Richard Schwab, MD, is Assistant Professor of Medicine in the Division of Hematology-Oncology. Ajit Varki, MD, is Distinguished Professor of Medicine and Cellular and Molecular Medicine, Co-Director of the Glycobiology Research and Training Center, and Co-Director of the UCSD/Salk Center for Academic Research and Training in Anthropogeny. Read the abstract of the published study in Cancer Research.

Call of the Riled

Stress Signal in Cancer Cells Triggers Similar Response in Other Cells, Aiding Tumor Growth

Researchers at the University of California, San Diego School of Medicine say a “stress response” mechanism used by normal cells to cope with harsh or demanding conditions is exploited by cancer cells, which transmit the same stress signal to surrounding cells, triggering an inflammatory response in them that can aid tumor growth…. Read the full story from the UCSD Newsroom


Dr. Maurizio ZanettiDr. Maurizio Zanetti, pictured at left, is senior author of the study. Maurizio Zanetti, MD, is Emeritus Professor of Medicine in the Division of Hematology-Oncology and Director of the Laboratory of Immunology at UC San Diego Moores Cancer Center|  Read the abstract of the published report in PNAS.

UC San Diego Health System Expands Cancer-Related Services in North Coastal Area

San Diego Cancer Center patients will now have access to dozens of clinical trials

UC San Diego Health System is expanding its services in the North Coastal Community and is acquiring San Diego Cancer Center (SDCC). This acquisition is effective February 7, 2011. … Read the full story from the UC San Diego Newsroom

Dr. Barbara Parker, Medical Director of the UC San Diego Moores Cancer Center, is Professor of Clinical Medicine in the Division of Hematology-Oncology.