Researchers at the University of California, San Diego School of Medicine have identified 13 metabolites – small molecules produced by cellular metabolism – that are significantly different in patients with diabetes and chronic kidney disease compared to healthy controls. … Read the full story from the UC San Diego News Center
First author Kumar Sharma, MD, FAHA, is professor of medicine and director of the Center for Renal Translational Medicine in the Division of Nephrology-Hypertension.
Citation for the study report:
Metabolomics Reveals Signature of Mitochondrial Dysfunction in Diabetic Kidney Disease. Kumar Sharma, Bethany Karl, Anna V. Mathew, Jon A. Gangoiti, Christina L. Wassel, Rintaro Saito, Minya Pu, Shoba Sharma, Young-Hyun You, Lin Wang, Maggie Diamond-Stanic, Maja T. Lindenmeyer, Carol Forsblom, Wei Wu, Joachim H. Ix, Trey Ideker, Jeffrey B. Kopp, Sanjay K. Nigam, Clemens D. Cohen, Per-Henrik Groop, Bruce A. Barshop, Loki Natarajan, William L. Nyhan, and Robert K. Naviaux JASN ASN.2013020126; published ahead of print October 10, 2013, doi:10.1681/ASN.2013020126 | Full text (UCSD only)
Related UC San Diego news stories:
- $5.9 Million Grant to UC San Diego for Paradigm-Shifting Diabetes Research
- Drug Effective in Treating Kidney Disease in Diabetic Patients
- UCSD Nephrology Teaming with University of Alabama in O’Brien Center Grant
- Dr. Kumar Sharma and Coworkers Find Potential for Protecting Obese Patients from Heart and Kidney Disease